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[心肌病患者的室性快速性心律失常]

[Ventricular tachyarrhythmias in patients with cardiomyopathy].

作者信息

Henningsen Kristoffer, Christensen Alex Hørby, Svendsen Jesper Hastrup

机构信息

Kardiologisk Klinik B, Hjertecentret, Rigshospitalet, DK-2100 København Ø.

出版信息

Ugeskr Laeger. 2008 Jun 16;170(25):2238-42.

Abstract

INTRODUCTION

The purpose of this study was to determine the number and distribution of cardiomyopathies as the aetiology of ventricular tachyarrhythmias among patients discharged from the Department of Cardiology, Rigshospitalet.

MATERIALS AND METHODS

The study was a retrospective review of patients discharged with the diagnostic codes ventricular tachycardia, ventricular fibrillation or premature ventricular contractions with cardiomyopathy as the presumed aetiology. Patients discharged during a period of 6 years and 5 months were included in the study. The patients were characterized by disease, gender, age, previous cardiac arrest and treatment with implantable cardioverter-defibrillator (ICD).

RESULTS

993 patients were screened and 128 patients with cardiomyopathy were identified, corresponding to 13% of the screened patients. 58 (45%) of the patients had dilated cardiomyopathy (DCM), 57 (45%) patients had arrhythmogenic right ventricular cardiomyopathy (ARVC) and 13 (10%) had hypertrophic cardiomyopathy (HCM). The average age was 44 years for HCM, 41 years for ARVC and 58 years for DCM. The majority of the patients were male. ICD treatment was used in 95% of the patients with ARVC, 70% of the patients with HCM and 59% of the patients with DCM. Only 5 patients had previous cardiac arrest without reversible cause.

CONCLUSION

The study shows that cardiomyopathies are relatively frequent causes of ventricular tachyarrhythmias in patients discharged from a specialised cardiology department. Implantation of an ICD device has a central position in the treatment of patients with cardiomyopathy and ventricular tachyarrythmias and is primarily used as a prophylactic treatment.

摘要

引言

本研究的目的是确定在里格霍斯皮塔利特心脏病科出院患者中,作为室性快速心律失常病因的心肌病的数量和分布情况。

材料与方法

本研究是对诊断代码为室性心动过速、心室颤动或室性早搏且病因推测为心肌病的出院患者进行的回顾性研究。纳入了在6年零5个月期间出院的患者。对患者的疾病、性别、年龄、既往心脏骤停情况以及植入式心脏复律除颤器(ICD)治疗情况进行了特征分析。

结果

共筛查了993例患者,确定了128例患有心肌病的患者,占筛查患者的13%。其中58例(45%)患者患有扩张型心肌病(DCM),57例(45%)患者患有致心律失常性右室心肌病(ARVC),13例(10%)患有肥厚型心肌病(HCM)。HCM患者的平均年龄为44岁,ARVC患者为41岁,DCM患者为58岁。大多数患者为男性。95%的ARVC患者、70%的HCM患者和59%的DCM患者接受了ICD治疗。只有5例患者曾发生无可逆病因的心脏骤停。

结论

该研究表明,在专科心脏病科出院患者中,心肌病是室性快速心律失常相对常见的病因。植入ICD装置在心肌病合并室性快速心律失常患者的治疗中占据核心地位,主要用作预防性治疗。

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