银掺杂磷酸盐玻璃对细菌生物膜生长的影响。
Effect of silver-doped phosphate-based glasses on bacterial biofilm growth.
作者信息
Valappil Sabeel P, Knowles Jonathan C, Wilson Michael
机构信息
Division of Biomaterials and Tissue Engineering, University College London, London, United Kingdom.
出版信息
Appl Environ Microbiol. 2008 Aug;74(16):5228-30. doi: 10.1128/AEM.00086-08. Epub 2008 Jun 20.
Abstract
Silver-containing phosphate-based glasses were found to reduce the growth of Pseudomonas aeruginosa and Staphylococcus aureus biofilms, which are leading causes of nosocomial infections. The rates of glass degradation (1.27 to 1.41 microg.mm(-2).h(-1)) and the corresponding silver release were found to account for the variation in biofilm growth inhibitory effect.
摘要
含银磷酸盐玻璃被发现可减少铜绿假单胞菌和金黄色葡萄球菌生物膜的生长，而这两种生物膜是医院感染的主要原因。玻璃的降解速率（1.27至1.41微克·毫米⁻²·小时⁻¹）及相应的银释放量被发现可解释生物膜生长抑制效果的差异。
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