手机辐射后大鼠大脑中特定mRNA水平的上调。

Upregulation of specific mRNA levels in rat brain after cell phone exposure.

作者信息

Yan Ji-Geng, Agresti Michael, Zhang Lin-Ling, Yan Yuhui, Matloub Hani S

机构信息

Department of Plastic and Reconstructive Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

出版信息

Electromagn Biol Med. 2008;27(2):147-54. doi: 10.1080/15368370802072208.

DOI:10.1080/15368370802072208

PMID:18568932

Abstract

Adult Sprague-Dawley rats were exposed to regular cell phones for 6 h per day for 126 days (18 weeks). RT-PCR was used to investigate the changes in levels of mRNA synthesis of several injury-associated proteins. Calcium ATPase, Neural Cell Adhesion Molecule, Neural Growth Factor, and Vascular Endothelial Growth Factor were evaluated. The results showed statistically significant mRNA up-regulation of these proteins in the brains of rats exposed to cell phone radiation. These results indicate that relative chronic exposure to cell phone microwave radiation may result in cumulative injuries that could eventually lead to clinically significant neurological damage.

摘要

成年Sprague-Dawley大鼠每天暴露于普通手机辐射下6小时，持续126天（18周）。采用逆转录聚合酶链反应（RT-PCR）研究几种损伤相关蛋白的mRNA合成水平变化。对钙ATP酶、神经细胞黏附分子、神经生长因子和血管内皮生长因子进行了评估。结果显示，暴露于手机辐射的大鼠大脑中这些蛋白的mRNA出现了具有统计学意义的上调。这些结果表明，相对长期暴露于手机微波辐射可能导致累积性损伤，最终可能导致具有临床意义的神经损伤。