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手机辐射暴露对 Wistar 大鼠空间记忆能力的影响

Spatial memory performance of Wistar rats exposed to mobile phone.

机构信息

Department of Physiology, Melaka Manipal Medical College - Manipal, India.

出版信息

Clinics (Sao Paulo). 2009;64(3):231-4. doi: 10.1590/s1807-59322009000300014.

Abstract

INTRODUCTION

With the tremendous increase in number of mobile phone users world wide, the possible risks of this technology have become a serious concern.

OBJECTIVE

We tested the effects of mobile phone exposure on spatial memory performance.

MATERIALS AND METHODS

Male Wistar rats (10-12 weeks old) were exposed to 50 missed calls/day for 4 weeks from a GSM (900/1800 MHz) mobile phone in vibratory mode (no ring tone). After the experimental period, the animals were tested for spatial memory performance using the Morris water maze test.

RESULTS

Both phone exposed and control animals showed a significant decrease in escape time with training. Phone exposed animals had significantly (approximately 3 times) higher mean latency to reach the target quadrant and spent significantly (approximately 2 times) less time in the target quadrant than age- and sex-matched controls.

CONCLUSION

Mobile phone exposure affected the acquisition of learned responses in Wistar rats. This in turn points to the poor spatial navigation and the object place configurations of the phone-exposed animals.

摘要

简介

随着全球移动电话用户数量的巨大增长,这项技术的潜在风险已成为一个严重的关注点。

目的

我们测试了手机暴露对空间记忆性能的影响。

材料与方法

雄性 Wistar 大鼠(10-12 周龄)在振动模式下(无振铃声)每天接受 50 个未接来电,持续 4 周,来自 GSM(900/1800MHz)手机。实验期结束后,使用 Morris 水迷宫测试评估动物的空间记忆性能。

结果

手机暴露组和对照组动物在训练过程中均明显缩短了逃避时间。与年龄和性别匹配的对照组相比,手机暴露组动物到达目标象限的平均潜伏期显著升高(约 3 倍),并且在目标象限中花费的时间显著减少(约 2 倍)。

结论

手机暴露影响了 Wistar 大鼠习得反应的获得。这反过来又表明,暴露于手机的动物在空间导航和物体位置配置方面较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd42/2666459/9744bc9732a3/14-br-0235f1.jpg

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