Miller Vivien, Whorwell Peter J
University of Manchester, United Kingdom.
Int J Clin Exp Hypn. 2008 Jul;56(3):306-17. doi: 10.1080/00207140802041884.
Fifteen patients with severe or very severe inflammatory bowel disease on corticosteroids but not responding to medication received 12 sessions of "gut-focused hypnotherapy" and were followed up for a mean duration of 5.4 years with disease severity being graded as remission, mild, moderate, severe, or very severe. Two patients (13.4%) failed to respond and required surgery. At follow-up for the remaining 13 patients, 4 (26.6%) were in complete remission, 8 (53.3%) had mild severity, and 1 (6.7%) was moderately severe. Quality of life became good or excellent in 12 (79.9%). Corticosteroid requirements dramatically declined with 60% of patients stopping them completely and not requiring any during follow-up. Hypnotherapy appears to be a promising adjunctive treatment for inflammatory bowel disease and has steroid sparing effects. Controlled trials to clearly define its role in this disease area are justified.
15名患有严重或极严重炎症性肠病且正在使用皮质类固醇但对药物治疗无反应的患者接受了12次“专注肠道的催眠疗法”,并进行了平均5.4年的随访,疾病严重程度分为缓解、轻度、中度、重度或极重度。两名患者(13.4%)无反应,需要手术。在对其余13名患者的随访中,4名(26.6%)完全缓解,8名(53.3%)病情轻度,1名(6.7%)病情中度。12名患者(79.9%)的生活质量良好或极佳。皮质类固醇的需求量大幅下降,60%的患者在随访期间完全停用且不再需要使用。催眠疗法似乎是炎症性肠病一种有前景的辅助治疗方法,且具有节省类固醇的作用。进行对照试验以明确其在该疾病领域的作用是合理的。