Almeida A F, Nation P N, Guidotti T L
Department of Public Health Sciences, Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Int J Toxicol. 2008;27(3):287-93. doi: 10.1080/10915810802210166.
Sodium hydrosulfide and dimethylsulfide duplicate the effects of hydrogen sulfide in causing coma in Sprague-Dawley rats and are additive for lethality. Nitrite, pyruvate and dithiothreitol had no significant effect on coma or lethality but bicarbonate with and without glucose reduced duration of coma. This finding suggests an antidotal treatment.
氢硫化钠和二甲基硫醚可复制硫化氢导致斯普拉格-道利大鼠昏迷的作用，且对致死性有相加作用。亚硝酸盐、丙酮酸和二硫苏糖醇对昏迷或致死性无显著影响，但有无葡萄糖的碳酸氢盐均可缩短昏迷持续时间。这一发现提示了一种解毒治疗方法。
