Smits Frans Th M, Wittkampf Karin A, Schene Aart H, Bindels Patrick J E, Van Weert Henk C P M
Department of General Practice Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Scand J Prim Health Care. 2008;26(2):111-6. doi: 10.1080/02813430802112997.
To analyse which interventions are effective in influencing morbidity, quality of life, and healthcare utilization of frequently attending patients (FAs) in primary care.
A systematic literature search was performed for articles describing interventions on FAs in primary care (Medline, Embase, and PsycINFO). Outcomes were morbidity, quality of life (QoL), and use of healthcare. Two independent assessors selected all randomized clinical trials (RCT) and assessed the quality of the selected RCTs. Results. Five primary care based RCTs were identified. Three RCTs used frequent attendance to select patients at risk of distress, major depression, and anxiety disorders. These RCTs applied psychological and psychiatric interventions and focused on undiagnosed psychiatric morbidity of FAs. Two of them found more depression-free days and a better QoL after treating major depressive disorder in FAs. No other RCT found any positive effect on morbidity or QoL. Two RCTs studied an intervention which focused on reducing frequent attendance. No intervention significantly lowered attendance. Due to the difference in study settings and the variation in methods of selecting patients, meta-analysis of the results was not possible.
No study showed convincing evidence that an intervention improves QoL or morbidity of frequent attending primary care patients, although a small effect might be possible in a subgroup of depressed frequent attenders. No evidence was found that it is possible to influence healthcare utilization of FAs.
分析哪些干预措施能有效影响基层医疗中频繁就诊患者(FAs)的发病率、生活质量和医疗保健利用率。
对描述基层医疗中针对FAs干预措施的文章进行系统文献检索(检索数据库包括Medline、Embase和PsycINFO)。结局指标为发病率、生活质量(QoL)和医疗保健使用情况。两名独立评估者筛选所有随机临床试验(RCT)并评估所选RCT的质量。结果。共识别出五项基于基层医疗的RCT。三项RCT利用频繁就诊情况筛选有痛苦、重度抑郁和焦虑症风险的患者。这些RCT采用心理和精神科干预措施,重点关注FAs未确诊的精神疾病发病率。其中两项研究发现,对FAs的重度抑郁症进行治疗后,无抑郁天数增多,生活质量改善。其他RCT均未发现对发病率或生活质量有任何积极影响。两项RCT研究了一项旨在减少频繁就诊的干预措施。没有干预措施能显著降低就诊率。由于研究背景不同以及患者选择方法存在差异,无法对结果进行荟萃分析。
没有研究显示有令人信服的证据表明某项干预措施能改善基层医疗频繁就诊患者的生活质量或发病率,尽管在抑郁频繁就诊患者亚组中可能有微小效果。未发现有证据表明可以影响FAs的医疗保健利用率。