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[根据诊断类别,重症监护病房后健康相关生活质量的变化。两种测量工具的比较]

[Changes in health-related quality of life after ICU according to diagnostic category. Comparison of two measurement instruments].

作者信息

Badia Castelló M, Trujillano Cabello J, Serviá Goixart L, March Llanes J, Rodríguez-Pozo A

机构信息

Servicio de Medicina Intensiva, Hospital Universitario Arnau de Vilanova, Lleida, España.

出版信息

Med Intensiva. 2008 Jun-Jul;32(5):203-15. doi: 10.1016/s0210-5691(08)70942-2.

DOI:10.1016/s0210-5691(08)70942-2
PMID:18570830
Abstract

OBJECTIVE

Assessment of health related quality of life (HRQOL) before and 12 months after discharge from a mixed intensive care unit (ICU) according to diagnostic category and the relationship between both instruments.

DESIGN

Prospective observational study.

SETTING

The combined medical/surgical ICU in a secondary university hospital with 450 beds.

PATIENTS

Patients admitted to the ICU over an 18-month period.

MAIN VARIABLES

Variables on demography, diagnosis on admission, severity of acute illness score (APACHE II), length of stay, procedures, mortality and the HRQOL were collected using the Short Form SF-36 and EQ-5D questionnaires. Health status prior to admission was evaluated retrospectively.

RESULTS

Both questionnaires were answered by 189 patients. A significant deterioration in the quality of life was observed 12 months after ICU discharge. Head injury and neurological patients had worse HRQOL one year after discharge. Multiple trauma patients presented severe physical limitations and pain, but without significant differences on the emotional level. The EQ Visual Analogue Scale and the EQ Index score showed clinically relevant differences in these three groups. Respiratory patients are the only group in whom the HRQOL improved. Comparison between both measurement instruments showed a strong correlation on the physical functioning level, but a weaker correlation on the emotional functioning one.

CONCLUSIONS

HRQOL assessment of ICU patients must be done according to a diagnostic category. Both instruments (the EQ-5D and SF-36) are capable of detecting changes in HRQOL. Despite differences in structure and content, both measure similar aspects of quality of life.

摘要

目的

根据诊断类别评估混合重症监护病房(ICU)出院前及出院12个月后的健康相关生活质量(HRQOL),以及两种评估工具之间的关系。

设计

前瞻性观察性研究。

地点

一所拥有450张床位的二级大学附属医院的内科/外科联合ICU。

患者

18个月内入住ICU的患者。

主要变量

使用简短健康调查问卷SF - 36和欧洲五维度健康量表EQ - 5D收集人口统计学变量、入院诊断、急性疾病严重程度评分(APACHE II)、住院时间、治疗程序、死亡率和HRQOL。回顾性评估入院前的健康状况。

结果

189名患者完成了两份问卷。观察到ICU出院12个月后生活质量显著下降。颅脑损伤和神经科患者出院一年后HRQOL较差。多发伤患者存在严重的身体限制和疼痛,但在情感层面无显著差异。EQ视觉模拟量表和EQ指数评分在这三组中显示出临床相关差异。呼吸系统疾病患者是HRQOL有所改善的唯一一组。两种测量工具之间的比较显示,在身体功能水平上相关性较强,但在情感功能水平上相关性较弱。

结论

必须根据诊断类别对ICU患者进行HRQOL评估。两种工具(EQ - 5D和SF - 36)都能够检测HRQOL的变化。尽管在结构和内容上存在差异,但两者都测量了生活质量的相似方面。

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