Serviá Goixart L, Badia Castelló M, Montserrat Ortiz N, Bello Rodriguez G, Vicario Izquierdo E, Vilanova Corselles J, Trujillano Cabello J
Servicio de Medicina Intensiva, Hospital Universitario Arnau de Vilanova, Lleida, España.
Servicio de Medicina Intensiva, Hospital Universitario Arnau de Vilanova, Lleida, España.
Med Intensiva. 2014 Jan-Feb;38(1):1-10. doi: 10.1016/j.medin.2012.10.008. Epub 2013 Jan 8.
To evaluate factors influencing the deterioration of health-related quality of life (HRQoL) in trauma patients admitted to an ICU.
A prospective observational study was carried out.
The combined medical/surgical ICU in a university secondary hospital with 24-hour neurosurgery service.
Trauma patients admitted to the ICU during a two-year period. HRQoL assessment prior to admission to the ICU, and at 6 and 12 months after discharge.
Demographic variables, type and severity of injury (AIS), severity (APACHE II, ISS, TRISS), length of stay, procedures, mortality and HRQoL according to the SF-36 and EQ-5D.
We completed the monitoring of 110 patients that showed significant impairment of their HRQoL in all the dimensions assessed. According to the SF-36, physical role was more deteriorated at 12 months, but the mental component decreased more than the physical component after 6 months. The VAS scale of the EQ-5D decreased to 55 at 6 months (19) and increased to 66 at 12 months (17). In the multiple logistic regression analysis, the variables associated with poorer HRQoL were age > 45 years, TRISS > 10, previous porer quality of life, and serious injuries in the extremities.
Patients showed marked deterioration of their HRQoL at 6 months, followed by overall improvement at 12 months, though without reaching their previous state. The factors that determine poorer quality of life include age, severity, previous HRQoL, and severe injuries in the extremities.
评估影响入住重症监护病房(ICU)的创伤患者健康相关生活质量(HRQoL)恶化的因素。
开展一项前瞻性观察性研究。
一所拥有24小时神经外科服务的大学二级医院的内科/外科联合ICU。
在两年期间入住ICU的创伤患者。在入住ICU之前、出院后6个月和12个月进行HRQoL评估。
人口统计学变量、损伤类型和严重程度(AIS)、严重程度(急性生理与慢性健康状况评分系统II [APACHE II]、损伤严重度评分 [ISS]、创伤和损伤严重度评分 [TRISS])、住院时间、手术、死亡率以及根据简明健康状况调查量表(SF-36)和欧洲五维健康量表(EQ-5D)得出的HRQoL。
我们完成了对110例患者的监测,这些患者在所有评估维度中均显示出HRQoL的显著受损。根据SF-36,身体功能在12个月时恶化更为明显,但6个月后心理维度的下降幅度大于身体维度。EQ-5D的视觉模拟量表(VAS)在6个月时降至55(满分100),在12个月时升至66(满分100)。在多元逻辑回归分析中,与HRQoL较差相关的变量包括年龄>45岁、TRISS>10、既往生活质量较差以及四肢严重损伤。
患者在6个月时HRQoL显著恶化,随后在12个月时总体有所改善,尽管未恢复到之前的状态。决定生活质量较差的因素包括年龄、严重程度、既往HRQoL以及四肢严重损伤。