Torres-Rodríguez J M, Nicolás M C, Madrenys N, Gallach C
Departamento de Microbiología, Universitat Autònoma de Barcelona.
Med Clin (Barc). 1991 Jun 1;97(1):1-3.
Candida albicans is distributed in at least two serological groups (A and B) depending on its antigenic structure. These characteristics have been used to investigate the epidemiology of candidiasis. No information is available in this country about the distribution of these serotypes in a general population of patients with candidiasis of different localizations. The aim of the present study was to correlate the frequency of C. albicans serotypes with the origin of the clinical samples.
In 502 strains of C. albicans isolated from pathological products, serotype was evaluated by means of a latex agglutination test with polyclonal monovalent antisera. A statistical analysis was carried out to investigate whether there was any relationship between the serotype frequency and the origin of the strains.
The serotype A of C. albicans represented 78% of all isolates. However, there was a significantly higher relative frequency of serotype B in vaginal and oropharyngeal samples. No differences were found in isolates from AIDS patients.
The serotyping method should be considered a contribution, even if limited, to the knowledge of the epidemiology of Candida albicans infections.
白色念珠菌根据其抗原结构至少分布于两个血清学组（A组和B组）。这些特征已被用于研究念珠菌病的流行病学。该国尚无关于这些血清型在不同部位念珠菌病患者普通人群中分布情况的信息。本研究的目的是将白色念珠菌血清型的频率与临床样本的来源相关联。
在从病理产物中分离出的502株白色念珠菌菌株中，通过使用多克隆单价抗血清的乳胶凝集试验评估血清型。进行统计分析以研究血清型频率与菌株来源之间是否存在任何关系。
白色念珠菌的血清型A占所有分离株的78%。然而，在阴道和口咽样本中，血清型B的相对频率明显更高。在艾滋病患者的分离株中未发现差异。
血清分型方法应被视为对白色念珠菌感染流行病学知识的一种贡献，即使这种贡献有限。
