Caminero J A, Díaz F, Rodríguez de Castro F, Alonso J L, Daryanany R D, Carrillo T, Cabrera P
Sección de Neumología, Hospital Nuestra Señora del Pino, Las Palmas de Gran Canaria.
Med Clin (Barc). 1991 Jun 1;97(1):8-13.
The aim of the present study was to obtain information about tuberculosis (TB) in our area that might contribute to assess the status in Spain.
A meticulous case finding was carried out during 1988 in all the hospitals of the Gran Canaria island.
214 cases were found (rate 32.2) and 77% were admitted to hospitals. In 160 (74%) the involvement was pulmonary and in 82 (37%) it was extrapulmonary. Mean age was 34 years (range 1-84) and 62% were younger than 40 years. 69% were males. Complete data were obtained in 183 cases (85%). 56% were smokers, 34% alcoholic abusers, 15% drug abusers (35% parenteral) and 4% homosexuals. 26% had some risk factor for TB; 14 of them had been infected by the HIV (8 had AIDS). In 64% there was a diagnostic delay longer than one month. Out of the 214 cases, the diagnosis was made by direct microscopy and/or culture in 110 (51%), by consistent pathological findings in 41 (19%), with some of these studies but with negative results in 35 (16%) and only with clinical and radiological criteria in 28 (13%). 96 (60%) of the pulmonary cases had cavitation. The most common therapeutic schedule (84%) was the recommended 9-month regimen. In 54% no recommendation for the investigation of contacts was made.
In the authors' area, the prevalence of TB is higher than in developed countries. It is more common in middle aged individuals, many diagnoses are still made without bacteriologic studies and in a high number of cases investigation of contacts is not carried out.
本研究的目的是获取我们所在地区结核病（TB）的相关信息，这些信息可能有助于评估西班牙的结核病状况。
1988年在大加那利岛的所有医院进行了细致的病例查找。
共发现214例（发病率32.2），其中77%入院治疗。160例（74%）为肺部感染，82例（37%）为肺外感染。平均年龄为34岁（范围1 - 84岁），62%的患者年龄小于40岁。69%为男性。183例（85%）获得了完整数据。56%为吸烟者，34%有酗酒问题，15%为药物滥用者（35%为注射用药），4%为同性恋者。26%有结核病的某些危险因素；其中14例感染了艾滋病毒（8例患有艾滋病）。64%的患者诊断延迟超过1个月。在214例病例中，通过直接显微镜检查和/或培养确诊的有110例（51%），通过一致的病理检查结果确诊的有41例（19%），部分进行了这些检查但结果为阴性的有35例（16%），仅根据临床和影像学标准确诊的有28例（13%）。96例（60%）肺部病例有空洞形成。最常见的治疗方案（84%）是推荐的9个月疗程。54%的病例未对接触者进行调查建议。
在作者所在地区，结核病的患病率高于发达国家。在中年个体中更为常见，许多诊断仍未进行细菌学研究，并且在大量病例中未对接触者进行调查。
