Natural orifice transluminal endoscopic gastric bypass performed in a cadaver.

Natural orifice transluminal surgery (NOTES) offers a new option for abdominal surgery. However, despite the initial interest and enthusiasm for its potential advantages, NOTES has some major drawbacks which include the purposeful injury to an organ that may not be otherwise injured or diseased. Roux-en-Y gastric bypass may be a procedure that is suited for NOTES because the stomach wall is breached during the normal course of the operation. We have experimented with a technique for a NOTES gastric bypass in the human. A transvaginal, transgastric gastric bypass (TVTG-GBP) was performed in a human cadaver.