Kong F, Singh R P
Departmentt of Biological and Agricultural Engineering, University of California, Davis, CA 95616, USA.
J Food Sci. 2008 Jun;73(5):E202-10. doi: 10.1111/j.1750-3841.2008.00745.x.
Knowledge of the disintegration kinetics of food particulates in the human stomach is essential for assessing the bioaccessibility of nutrients in solid foods and understanding stomach emptying. The objective of this study was to develop a model stomach system and to investigate the kinetics of food disintegration. Our system consisted mainly of a turntable and a jacketed glass chamber containing simulated gastric juice in which plastic beads were added to simulate food particulates as well as provide a suitable mechanical destructive force on food samples. The mechanical force on the samples was simultaneously measured using the load cell of a TA-XT2 texture analyzer. Cylindrical carrots and ham samples were used as representative foods. The system is capable of simulating the in vivo stomach in terms of providing a wide range of continuous and periodic forces comparable to those measured in vivo. The modified power exponential function of the form y(t)= 1 - (1 -e(-kt))(beta), where y(t) is the mass retention ratio at time t, provided a reasonable description for the disintegration performance of tested foods. The mass retention curve can be either a sigmoidal decay with an initial delay or an exponential decay, which are decided largely by the hardness of the foods during digestion and the extent of physical force acting on the foods. A good match was observed between the kinetics of food disintegration and in vivo stomach emptying.
了解食物颗粒在人体胃中的崩解动力学对于评估固体食物中营养素的生物可及性以及理解胃排空至关重要。本研究的目的是开发一种模拟胃系统并研究食物崩解动力学。我们的系统主要由一个转盘和一个夹套玻璃腔室组成，腔室内装有模拟胃液，其中添加了塑料珠以模拟食物颗粒，并为食物样品提供适当的机械破坏力。使用TA-XT2质构分析仪的测力传感器同时测量样品上的机械力。圆柱形胡萝卜和火腿样品用作代表性食物。该系统能够模拟体内胃，提供与体内测量的力相当的广泛连续和周期性力。形式为y(t)= 1 - (1 -e(-kt))(beta)的修正幂指数函数，其中y(t)是时间t时的质量保留率，对测试食物的崩解性能提供了合理描述。质量保留曲线可以是具有初始延迟的S形衰减或指数衰减，这在很大程度上取决于消化过程中食物的硬度以及作用于食物的物理力的程度。观察到食物崩解动力学与体内胃排空之间有良好的匹配。
