Rochat Lucien, Delbeuck Xavier, Billieux Joël, d'Acremont Mathieu, Van der Linden Anne-Claude Juillerat, Van der Linden Martial
Cognitive Psychopathology and Neuropsychology Unit, University of Geneva, Geneva, Switzerland.
Alzheimer Dis Assoc Disord. 2008 Jul-Sep;22(3):278-83. doi: 10.1097/WAD.0b013e318166d692.
Impulsive behaviors are common in brain-damaged patients including those with neurodegenerative diseases such as Alzheimer disease (AD). The objective of this study was to develop and validate a short version of the UPPS Impulsive Behavior Scale assessing changes on 4 different dimensions of impulsivity, namely urgency, (lack of) premeditation, (lack of) perseverance, and sensation seeking, arising in the course of a neurodegenerative disease. To this end, caregivers of 83 probable AD patients completed a short questionnaire adapted from the UPPS Impulsive Behavior Scale. Exploratory and confirmatory factor analyses of the data were performed and revealed that a model with 4 distinct but related latent variables corresponding to 4 different dimensions of impulsivity fit the data best. Furthermore, the results showed that lack of perseverance, followed by lack of premeditation and urgency, increased after the onset of the disease, whereas sensation seeking decreased. Overall, the multifaceted nature of impulsivity was confirmed in a sample of AD patients, whose caregivers reported significant changes regarding each facet of impulsivity. Consequently, the short version of the UPPS Impulsive Behavior Scale opens up interesting prospects for a better comprehension of behavioral symptoms of dementia.
冲动行为在脑损伤患者中很常见，包括患有神经退行性疾病（如阿尔茨海默病，AD）的患者。本研究的目的是开发并验证一个简短版的UPPS冲动行为量表，以评估神经退行性疾病过程中出现的冲动性的4个不同维度的变化，即冲动性、（缺乏）预谋、（缺乏）坚持性和寻求刺激。为此，83名可能患有AD的患者的照料者完成了一份改编自UPPS冲动行为量表的简短问卷。对数据进行探索性和验证性因素分析，结果显示，一个具有4个不同但相关的潜在变量、对应冲动性4个不同维度的模型最适合这些数据。此外，结果表明，疾病发作后，缺乏坚持性增加，其次是缺乏预谋和冲动性，而寻求刺激减少。总体而言，AD患者样本证实了冲动性的多面性，其照料者报告了冲动性各方面的显著变化。因此，UPPS冲动行为量表的简短版为更好地理解痴呆症的行为症状开辟了有趣的前景。
