Jayaraman Girija
Centre for Atmospherics Sciences, Indian Institute of Technology Delhi, New Delhi 110 016, India.
Health Care Manag Sci. 2008 Jun;11(2):132-8. doi: 10.1007/s10729-007-9050-7.
As a rapidly expanding centre of government, trade, commerce and industry, Delhi, the Indian capital, presents an instructive location for studying the possible association between air pollution and adverse health effects. This study tries to determine the association, if any, between the air pollutants--sulphur dioxide, nitrogen dioxide, carbon monoxide, ozone, suspended particulate matter and respiratory suspended particulate matter--and daily variations in respiratory morbidity in Delhi during the years 2004--2005. Data analysis was based on the Generalized Additive Poisson regression model including a Lowess smoothing function for the entire patient population and subgroups defined by season. The best fitting lag period for each pollutant was found by testing its concentration at varying lags. The model demonstrated associations between daily visits and some of the pollutants (O3, NO2 and RSPM) but their strongest components were observed at varying lags. A single pollutant model showed that a 10 microg m(-3) rise in pollutant level led to statistically significant relative risks (RR): 1.033 for O3, 1.004 for NO2, 1.006 for RSPM. The effect of particulate was relatively low, presumably because unlike other pollutants, particulate matter is not a single pollutant but rather a class of pollutants. This study, continued on a long term basis, can provide guidelines for anticipation/preparedness in the management of health care and hospital admissions.
作为印度首都,德里是一个政府、贸易、商业和工业迅速扩张的中心,是研究空气污染与不良健康影响之间可能关联的一个具有启发性的地点。本研究试图确定2004 - 2005年期间德里的空气污染物(二氧化硫、二氧化氮、一氧化碳、臭氧、悬浮颗粒物和呼吸性悬浮颗粒物)与呼吸道发病率的每日变化之间是否存在关联。数据分析基于广义相加泊松回归模型,该模型包括针对全体患者人群以及按季节定义的亚组的局部加权散点平滑(Lowess)函数。通过测试不同滞后时间的污染物浓度,找到了每种污染物的最佳拟合滞后时间。该模型显示每日就诊次数与某些污染物(臭氧、二氧化氮和呼吸性悬浮颗粒物)之间存在关联,但它们的最强关联成分在不同的滞后时间被观察到。单一污染物模型显示,污染物水平每升高10微克/立方米会导致具有统计学意义的相对风险(RR):臭氧为1.033,二氧化氮为1.004,呼吸性悬浮颗粒物为1.006。颗粒物的影响相对较低,大概是因为与其他污染物不同,颗粒物不是单一污染物,而是一类污染物。长期持续进行这项研究可为医疗保健管理和医院收治的预期/准备工作提供指导方针。