Wong T W, Lau T S, Yu T S, Neller A, Wong S L, Tam W, Pang S W
Department of Community and Family Medicine, Chinese University of Hong Kong.
Occup Environ Med. 1999 Oct;56(10):679-83. doi: 10.1136/oem.56.10.679.
To investigate short term effects of concentrations of pollutants in ambient air on hospital admissions for cardiovascular and respiratory diseases in Hong Kong.
Retrospective ecological study. A Poisson regression was performed of concentrations of daily air pollutant on daily counts of emergency hospital admissions in 12 major hospitals. The effects of time trend, season, and other cyclical factors, temperature, and humidity were accounted for. Autocorrelation and overdispersion were corrected. Daily concentrations of nitrogen dioxide (NO2), sulphur dioxide (SO2), ozone (O3), and particulate matter < 10 microns in aerodynamic diameter (PM10) were obtained from seven air monitoring stations in Hong Kong in 1994 and 1995. Relative risks (RR) of respiratory and cardiovascular disease admissions (for an increase of 10 micrograms/m3 in concentration of air pollutant) were calculated.
Significant associations were found between hospital admissions for all respiratory diseases, all cardiovascular diseases, chronic obstructive pulmonary diseases, and heart failure and the concentrations of all four pollutants. Admissions for asthma, pneumonia, and influenza were significantly associated with NO2, O3, and PM10. Relative risk (RR) for admissions for respiratory disease for the four pollutants ranged from 1.013 (for SO2) to 1.022 (for O3), and for admissions for cardiovascular disease, from 1.006 (for PM10) to 1.016 (for SO2). Those aged > or = 65 years were at higher risk. Significant positive interactions were detected between NO2, O3, and PM10, and between O3 and winter months.
Adverse health effects are evident at current ambient concentrations of air pollutants. Further reduction in air pollution is necessary to protect the health of the community, especially that of the high risk group.
研究香港环境空气中污染物浓度对心血管和呼吸系统疾病住院率的短期影响。
回顾性生态学研究。对12家主要医院每日急诊住院人数与每日空气污染物浓度进行泊松回归分析。考虑了时间趋势、季节和其他周期性因素、温度及湿度的影响。对自相关和过度离散进行了校正。1994年和1995年从香港7个空气监测站获取了二氧化氮(NO2)、二氧化硫(SO2)、臭氧(O3)和空气动力学直径小于10微米的颗粒物(PM10)的每日浓度。计算了空气污染物浓度每增加10微克/立方米时呼吸系统和心血管疾病住院的相对风险(RR)。
发现所有呼吸系统疾病、所有心血管疾病、慢性阻塞性肺疾病和心力衰竭的住院率与所有四种污染物的浓度之间存在显著关联。哮喘、肺炎和流感的住院率与NO2、O3和PM10显著相关。四种污染物导致呼吸系统疾病住院的相对风险(RR)范围为从1.013(SO2)到1.022(O3),心血管疾病住院的相对风险范围为从1.006(PM10)到1.016(SO2)。年龄≥65岁者风险更高。在NO2、O3和PM10之间以及O3与冬季月份之间检测到显著的正交互作用。
在当前环境空气污染物浓度下,对健康的不良影响明显。有必要进一步减少空气污染以保护社区健康,尤其是高危人群的健康。