Eneroth-Grimfors E, Lindblad L E, Westgren M, Etzell B M, Bevegård S
Department of Obstetrics and Gynecology, Södersjukhuset, Stockholm, Sweden.
Acta Obstet Gynecol Scand. 1991;70(1):25-8. doi: 10.3109/00016349109006173.
The aim of this study was to evaluate whether iontophoretic administration of the vasoactive agents noradrenaline (NA) and angiotensin (AII) combined with measurement of skin blood flow with a laser Doppler technique could serve as a predictive method for pre-eclampsia. Nine healthy non-pregnant women, 9 healthy pregnant women and 9 pre-eclamptic patients were investigated. A significant reduction of skin blood flow was induced by NA in all three groups and by AII in the non-pregnant group. There was no significant difference between healthy pregnant and pre-eclamptic patients in the degree of reduction of blood flow with respect to NA and AII administration.
本研究的目的是评估血管活性药物去甲肾上腺素（NA）和血管紧张素（AII）的离子电渗疗法联合激光多普勒技术测量皮肤血流是否可作为子痫前期的预测方法。对9名健康非孕妇、9名健康孕妇和9名子痫前期患者进行了研究。NA在所有三组中均引起皮肤血流显著减少，AII在非孕妇组中引起皮肤血流显著减少。在给予NA和AII后，健康孕妇和子痫前期患者的血流减少程度无显著差异。
