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不同炮制方法制得的制何首乌对血虚大鼠模型的影响

[Effect of Radix Polygoni Multifori praeparata by different processing on model of blood deficiency rats].

作者信息

Qiu Xiao-hui, Song Yan-gang, Sun Jing-bo, Min Jiang

机构信息

The Second College of Clinnic Medicine of Guangzhou University of TCM, Guangdong Guangzhou 510120, China.

出版信息

Zhong Yao Cai. 2008 Jan;31(1):14-7.

Abstract

OBJECTIVE

To evaluate a proper processed method of Radix Polygoni Multiflori by pharmacodynamic action.

METHODS

Model of blood deficiency rats were used in this experiment. The reagents were alcohol extracts of radix polygoni multiflori and its dreferent processing drugs made without any adjuvants in the first experiment. The reagents were alcohol extracts of te processing drugs made without any adjuvants and that made with decoction of black soybean in the second experiment. Their effecacy on model blood deficiency rats was observed.

RESULTS

It was showed that some of radix polygoni multiflori praeparata could nourish the blood. The effecacy was different for alcohol extracts of variously processing drugs. Decoction of black soybean could reinforce effectiveness of radix polygoni multiflori praeparata. But it was related to the processed method.

CONCLUSION

The processed method directly influences the pharmacodynamic action of radix polygoni multiflori praeparata.

摘要

目的

通过药效学作用评价何首乌的一种合适炮制方法。

方法

本实验采用血虚大鼠模型。在第一个实验中,试剂为何首乌及其不同炮制品的醇提取物,未添加任何辅料。在第二个实验中,试剂为未添加任何辅料的炮制品醇提取物和用黑豆汁炮制的炮制品醇提取物。观察它们对血虚模型大鼠的疗效。

结果

结果表明,部分制何首乌能补血。不同炮制品的醇提取物疗效不同。黑豆汁能增强制何首乌的功效。但这与炮制方法有关。

结论

炮制方法直接影响制何首乌的药效学作用。

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