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糖尿病性神经病变性关节病中的踝关节骨折:胫距关节融合术能否挽救肢体?

Ankle fractures in diabetic neuropathic arthropathy: can tibiotalar arthrodesis salvage the limb?

作者信息

Ayoub M A

机构信息

Department of Orthopaedic Surgery and Traumatology, Faculty of Medicine, University of Tanta, Al-Geish Street, Tanta, Egypt.

出版信息

J Bone Joint Surg Br. 2008 Jul;90(7):906-14. doi: 10.1302/0301-620X.90B7.20090.

Abstract

Between 2000 and 2006 we performed salvage tibiotalar arthrodesis in 17 diabetic patients (17 ankles) with grossly unstable ankles caused by bimalleolar fractures complicated by Charcot neuro-arthropathy. There were ten women and seven men with a mean age of 61.6 years (57 to 69). A crossed-screw technique was used. Two screws were used in eight patients and three screws in nine. Additional graft from the malleoli was used in all patients. The mean follow-up was 26 months (12 to 48) and the mean time to union was 5.8 months (4 to 8). A stable ankle was achieved in 14 patients (82.4%), nine of whom had bony fusion and five had a stiff fibrous union. The results were significantly better in underweight patients, in those in whom surgery had been performed three to six months after the onset of acute Charcot arthropathy, in those who had received anti-resorptive medication during the acute stage, in those without extensive peripheral neuropathy, and in those with adequate peripheral oxygen saturation (> 95%). The arthrodesis failed because of avascular necrosis of the talus in only three patients (17.6%), who developed grossly unstable, ulcerated hindfeet, and required below-knee amputation.

摘要

2000年至2006年间,我们对17例糖尿病患者(17个踝关节)进行了挽救性胫距关节融合术,这些患者因双踝骨折并发夏科特神经关节病而导致踝关节严重不稳定。其中有10名女性和7名男性,平均年龄为61.6岁(57至69岁)。采用了交叉螺钉技术。8例患者使用了2枚螺钉,9例患者使用了3枚螺钉。所有患者均使用了来自内、外踝的额外植骨。平均随访时间为26个月(12至48个月),平均愈合时间为5.8个月(4至8个月)。14例患者(82.4%)实现了踝关节稳定,其中9例获得了骨性融合,5例获得了牢固的纤维性融合。体重过轻的患者、在急性夏科特关节病发作后三至六个月接受手术的患者、在急性期接受抗吸收药物治疗的患者、没有广泛周围神经病变的患者以及外周血氧饱和度充足(>95%)的患者,其结果明显更好。仅3例患者(17.6%)因距骨缺血性坏死导致关节融合失败,这些患者出现了严重不稳定、溃疡的后足,需要进行膝下截肢。

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