Ha Joon, Hester Thomas, Foley Robert, Reichert Ines L H, Vas Prashanth R J, Ahluwalia Raju, Kavarthapu Venu
Department of Orthopaedics, King's College Hospital NHS Trust, London, United Kingdom.
King's Diabetic Foot Clinic, King's College College Hospital, London.
J Clin Orthop Trauma. 2020 May-Jun;11(3):357-368. doi: 10.1016/j.jcot.2020.03.025. Epub 2020 Apr 20.
Charcot neuroarthropathy is a complex condition characterised by progressive deformity, limited treatment options and a high amputation rate. Surgical reconstruction of Charcot foot has been proposed as a method to preserve the foot. However, limited information exists on the different methods of reconstruction available, their outcomes and complications.
We systematically analysed published data from Jan 1993 to Dec 2018 to assess methods of fixation and associated outcomes for the surgical reconstruction in Charcot neuroarthropathy. Statistical analyses were undertaken to determine the amputation rates, return to ambulation and complications associated with these techniques.
A total of 1116 feet (1089 patients) were reported to have undergone reconstruction with significant heterogeneity in patient selection. Of these, 726 (65%) were reported to undergo internal fixation, 346 feet (31%) external fixation and 44 (4%) undergoing simultaneous internal and external fixation. No single technique demonstrated a significant benefit over the other. Overall, the bone fusion rate was 86.1%. Complications directly attributable to the technique employed were noted in 36% of individuals. The reported post-reconstruction amputation rate was only 5.5% with 91% apparently returning to ambulation.
Although no preferential method of fixation was identified, we find that the current options for surgical reconstruction could offer limb salvage with a low amputation risk in a highly selected population. However, the lack of controlled studies, inconsistent reporting of outcomes and heterogeneity of patient selection mean that the quality of evidence is low.
夏科氏神经关节病是一种复杂病症,其特征为进行性畸形、治疗选择有限且截肢率高。已提出对夏科氏足进行手术重建作为保留足部的一种方法。然而,关于可用的不同重建方法、其结果和并发症的信息有限。
我们系统分析了1993年1月至2018年12月发表的数据,以评估夏科氏神经关节病手术重建的固定方法及相关结果。进行统计分析以确定与这些技术相关的截肢率、恢复行走情况和并发症。
共报告1116只足(1089例患者)接受了重建,患者选择存在显著异质性。其中,726只足(65%)报告接受了内固定,346只足(31%)接受了外固定,44只足(4%)接受了内外固定联合治疗。没有单一技术显示出比其他技术有显著优势。总体而言,骨融合率为86.1%。36%的个体出现了直接归因于所采用技术的并发症。报告的重建后截肢率仅为5.5%,91%的患者显然恢复了行走。
虽然未确定优先的固定方法,但我们发现,目前的手术重建选择可以在经过严格筛选的人群中提供低截肢风险的肢体挽救。然而,缺乏对照研究、结果报告不一致以及患者选择的异质性意味着证据质量较低。