Levanova G F, Sidorova N N, Kashnikov S Iu, Mazepa V N, Arziaeva A N
Zh Mikrobiol Epidemiol Immunobiol. 2008 May-Jun(3):13-5.
Plasmid analysis of 46 strains of Shigella species confirmed the view about heterogeneity and variability of plasmids composition in these microorganisms. On the other hand,the presence of low-molecular, multiplicated extrachromosomal replicons, which were stable, was shown. Using them, it was possible to divide the Shigella isolates into two major plasmidovars, characterize them according to repertoire of the most stable plasmids and determine epidemically significant variants during sporadic and outbreak incidence of shigellosis in towns Nizhny Novgorod and Kstovo (Nizhny Novgorod region).
对46株志贺氏菌进行质粒分析,证实了这些微生物中质粒组成具有异质性和变异性的观点。另一方面,研究表明存在稳定的低分子、多拷贝的染色体外复制子。利用这些复制子,可将志贺氏菌分离株分为两个主要的质粒型,根据最稳定质粒的种类对其进行表征,并确定下诺夫哥罗德市和科斯沃市(下诺夫哥罗德州)志贺氏菌病散发和暴发期间具有流行病学意义的变异株。