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Evidence for improving palliative care at the end of life: a systematic review.临终时改善姑息治疗的证据:一项系统综述。
Ann Intern Med. 2008 Jan 15;148(2):147-59. doi: 10.7326/0003-4819-148-2-200801150-00010.
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Mortality as a measure of quality: implications for palliative and end-of-life care.作为质量衡量指标的死亡率:对姑息治疗和临终关怀的影响。
JAMA. 2007 Aug 15;298(7):802-4. doi: 10.1001/jama.298.7.802.
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Efficacy of the world health organization analgesic ladder to treat pain in end-stage renal disease.世界卫生组织镇痛阶梯治疗终末期肾病疼痛的疗效
J Am Soc Nephrol. 2006 Nov;17(11):3198-203. doi: 10.1681/ASN.2006050477. Epub 2006 Sep 20.
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Prevalence, severity, and importance of physical and emotional symptoms in chronic hemodialysis patients.慢性血液透析患者身体和情绪症状的患病率、严重程度及重要性
J Am Soc Nephrol. 2005 Aug;16(8):2487-94. doi: 10.1681/ASN.2005020157. Epub 2005 Jun 23.
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Palliative care in end-stage renal disease: focus on advance care planning, hospice referral, and bereavement.终末期肾病的姑息治疗:关注预先护理计划、临终关怀转诊及哀伤辅导。
Semin Dial. 2005 Mar-Apr;18(2):154-6. doi: 10.1111/j.1525-139X.2005.18208.x.
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The family perspective of ESRD deaths.终末期肾病死亡的家庭视角。
Am J Kidney Dis. 2005 Jan;45(1):154-61. doi: 10.1053/j.ajkd.2004.09.014.
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Clinical practice. Palliative care.临床实践。姑息治疗。
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Advance care planning.预先护理计划
N Engl J Med. 2004 Jan 1;350(1):7-8. doi: 10.1056/NEJMp038202.
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Pain in hemodialysis patients: prevalence, cause, severity, and management.血液透析患者的疼痛:患病率、病因、严重程度及管理
Am J Kidney Dis. 2003 Dec;42(6):1239-47. doi: 10.1053/j.ajkd.2003.08.025.
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The need for end-of-life care training in nephrology: national survey results of nephrology fellows.肾脏病学临终关怀培训的必要性:肾脏病学住院医师全国调查结果
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“意外”问题在识别高死亡率透析患者中的效用。

Utility of the "surprise" question to identify dialysis patients with high mortality.

作者信息

Moss Alvin H, Ganjoo Jesse, Sharma Sanjay, Gansor Julie, Senft Sharon, Weaner Barbara, Dalton Cheryl, MacKay Karen, Pellegrino Beth, Anantharaman Priya, Schmidt Rebecca

机构信息

Section of Nephrology, Department of Medicine, School of Medicine, West Virginia University, Morgantown, West Virginia 26506-9022, USA.

出版信息

Clin J Am Soc Nephrol. 2008 Sep;3(5):1379-84. doi: 10.2215/CJN.00940208. Epub 2008 Jul 2.

DOI:10.2215/CJN.00940208
PMID:18596118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2518805/
Abstract

BACKGROUND AND OBJECTIVES

Dialysis patients are increasingly characterized by older age, multiple comorbidities, and shortened life expectancy. This study investigated whether the "surprise" question, "Would I be surprised if this patient died in the next year?" identifies patients who are at high risk for early mortality.

DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This prospective cohort study of 147 patients in three hemodialysis dialysis units classified patients into "yes" and "no" groups on the basis of the "surprise" question response and tracked patient status (alive or dead) at 12 mo. Demographics, Charlson Comorbidity Index score, and Karnofsky Performance Status score were measured.

RESULTS

Initially, 34 (23%) patients were classified in the "no" group. Compared with the 113 patients in the "yes" group, the patients in the "no" group were older (72.5 +/- 12.8 versus 64.5 +/- 14.9), had a higher comorbidity score (7.1 +/- 2.3 versus 5.8 +/- 2.1), and had a lower performance status score (69.7 +/- 17.1 versus 81.6 +/- 15.8). At 12 mo, 22 (15%) patients had died; the mortality rate for the "no" group was 29.4% and for the "yes" group was 10.6%. The odds of dying within 1 yr for the patients in the "no" group were 3.5 times higher than for patients in the "yes" group, (odds ratio 3.507, 95% CI 1.356 to 9.067, P = 0.01).

CONCLUSIONS

The "surprise" question is effective in identifying sicker dialysis patients who have a high risk for early mortality and should receive priority for palliative care interventions.

摘要

背景与目的

透析患者的特点越来越表现为年龄较大、合并多种疾病且预期寿命缩短。本研究调查了“意外”问题,即“如果该患者在明年死亡,我会感到意外吗?”能否识别出早期死亡风险较高的患者。

设计、地点、参与者及测量方法:这项对三个血液透析单位的147例患者进行的前瞻性队列研究,根据“意外”问题的回答将患者分为“是”和“否”两组,并在12个月时跟踪患者状态(存活或死亡)。测量了人口统计学数据、查尔森合并症指数评分和卡诺夫斯基功能状态评分。

结果

最初,34例(23%)患者被归类为“否”组。与“是”组的113例患者相比,“否”组患者年龄更大(72.5±12.8岁对64.5±14.9岁),合并症评分更高(7.1±2.3对5.8±2.1),功能状态评分更低(69.7±17.1对81.6±15.8)。在12个月时,22例(15%)患者死亡;“否”组死亡率为29.4%,“是”组为10.6%。“否”组患者在1年内死亡的几率比“是”组患者高3.5倍(优势比3.507,95%可信区间1.356至9.067,P = 0.01)。

结论

“意外”问题能有效识别出病情较重、早期死亡风险较高且应优先接受姑息治疗干预的透析患者。