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结核分枝杆菌W-北京基因型菌株感染对台湾老年患者的临床影响。

Clinical impact of Mycobacterium tuberculosis W-Beijing genotype strain infection on aged patients in Taiwan.

作者信息

Feng Jia-Yih, Su Wei-Juin, Tsai Cheng-Chien, Chang Shi-Chuan

机构信息

Chest Department, Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

J Clin Microbiol. 2008 Sep;46(9):3127-9. doi: 10.1128/JCM.01132-08. Epub 2008 Jul 2.

DOI:10.1128/JCM.01132-08
PMID:18596137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2546746/
Abstract

The impact of W-Beijing genotype Mycobacterium tuberculosis on treatment outcome was evaluated in 249 newly diagnosed tuberculosis patients. No significant difference in the treatment outcome was found between the W-Beijing and non-W-Beijing groups. However, a poor outcome was more common in the elderly patients (>or=65 years) infected with the W-Beijing strain.

摘要

对249例新诊断的结核病患者评估了北京基因型结核分枝杆菌对治疗结果的影响。在北京基因型组和非北京基因型组之间未发现治疗结果有显著差异。然而，感染北京基因型菌株的老年患者（≥65岁）中不良结果更为常见。

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本文引用的文献

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Int J Tuberc Lung Dis. 2007 Oct;11(10):1087-93.
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Association between Mycobacterium tuberculosis Beijing/W lineage strain infection and extrathoracic tuberculosis: Insights from epidemiologic and clinical characterization of the three principal genetic groups of M. tuberculosis clinical isolates.结核分枝杆菌北京/W 家族菌株感染与胸外结核之间的关联：来自结核分枝杆菌临床分离株三个主要基因群的流行病学和临床特征分析
J Clin Microbiol. 2007 Feb;45(2):409-14. doi: 10.1128/JCM.01459-06. Epub 2006 Dec 13.
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Beijing genotype of Mycobacterium tuberculosis is significantly associated with human immunodeficiency virus infection and multidrug resistance in cases of tuberculous meningitis.结核分枝杆菌的北京基因型与结核性脑膜炎病例中的人类免疫缺陷病毒感染及多重耐药性显著相关。
J Clin Microbiol. 2006 Nov;44(11):3934-9. doi: 10.1128/JCM.01181-06. Epub 2006 Sep 13.
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Tuberculosis associated with Mycobacterium tuberculosis Beijing and non-Beijing genotypes: a clinical and immunological comparison.与结核分枝杆菌北京基因型和非北京基因型相关的结核病：临床和免疫学比较。
BMC Infect Dis. 2006 Jul 5;6:105. doi: 10.1186/1471-2334-6-105.
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