Farinon A M, Pacella A, Cetta F, Sianesi M
Chair of Surgical Pathology, II University of Rome, Italy.
HPB Surg. 1991 Apr;3(4):251-8. doi: 10.1155/1991/59324.
The finding of adenomatous polyps of the gallbladder is a rare occurrence and an unusual clinical problem. Among 2,145 patients who underwent cholecystectomy for gallbladder disease only 9 (0.4 per cent) presented with adenomatous polyps. There were 6 women and 3 men, aged 17 to 70 years. Preoperative ultrasonographic diagnosis was made in only 1 of 7 patients with gallstones, in contrast polypoid lesions within a gallbladder without stones were easily confirmed by both ultrasonography and oral cholecystography in the remaining 2 patients. All polyps were 1.0 cm or less in size and without histologic evidence of malignant change. The clinical significance of this rare condition is discussed, with particular reference to a possible role in development of gallbladder carcinoma. Surgical treatment should be advocated regardless of clinical manifestation when the polyp exceeds 1.0 cm in diameter or rapid growth of the lesion is seen on ultrasonographic follow-up examinations.
胆囊腺瘤性息肉的发现是一种罕见情况且是个不寻常的临床问题。在仅因胆囊疾病接受胆囊切除术的2145例患者中，仅有9例（0.4%）患有腺瘤性息肉。其中有6名女性和3名男性，年龄在17至70岁之间。7例有胆结石的患者中只有1例在术前通过超声做出诊断，相比之下，其余2例胆囊内无结石的息肉样病变通过超声和口服胆囊造影术都很容易得到确诊。所有息肉大小均在1.0厘米或以下，且无恶性变化的组织学证据。本文讨论了这种罕见病症的临床意义，特别提及了其在胆囊癌发生过程中可能扮演的角色。当息肉直径超过1.0厘米或在超声随访检查中发现病变快速生长时，无论临床表现如何，都应提倡手术治疗。
