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胆囊息肉:影响手术决策的因素。

Gallbladder polyps: factors affecting surgical decision.

机构信息

Department of General Surgery, Uludag University School of Medicine, Gorukle, 16059 Bursa, Turkey.

出版信息

World J Gastroenterol. 2013 Jul 28;19(28):4526-30. doi: 10.3748/wjg.v19.i28.4526.

Abstract

AIM

To determine the factors affecting the decision to perform surgery, and the efficiency of ultrasonography (USG) in detecting gallbladder polyps (GP).

METHODS

Data for 138 patients who underwent cholecystectomy between 1996 and 2012 in our clinic with a diagnosis of GP were retrospectively analyzed. Demographic data, clinical presentation, principal symptoms, ultrasonographic and histopathological findings were evaluated. Patients were evaluated in individual groups according to the age of the patients (older or younger than 50 years old) and polyp size (bigger or smaller than 10 mm) and characteristics of the polyps (pseudopolyp or real polyps). χ(2) tests were used for the statistical evaluation of the data.

RESULTS

The median age was 50 (26-85) years and 91 of patients were female. Of 138 patients who underwent cholecystectomy with GP diagnosis, only 99 had a histopathologically defined polyp; 77 of them had pseudopolyps and 22 had true polyps. Twenty-one patients had adenocarcinoma. Of these 21 patients, 11 were male, their median age was 61 (40-85) years and all malignant polyps had diameters > 10 mm (P < 0.0001). Of 138 patients in whom surgery were performed, 112 had ultrasonographic polyps with diameters < 10 mm. Of the other 26 patients who also had polyps with diameters > 10 mm, 22 had true polyps. The sensitivity of USG was 84.6% for polyps with diameters > 10 mm (P < 0.0001); however it was only 66% in polyps with diameters < 10 mm.

CONCLUSION

The risk of malignancy was high in the patients over 50 years old who had single polyps with diameters > 10 mm.

摘要

目的

确定影响手术决策的因素,以及超声(USG)检测胆囊息肉(GP)的效率。

方法

回顾性分析了 1996 年至 2012 年在我院因 GP 接受胆囊切除术的 138 例患者的数据。评估了人口统计学数据、临床表现、主要症状、超声和组织病理学发现。根据患者年龄(大于或小于 50 岁)和息肉大小(大于或小于 10mm)以及息肉特征(假息肉或真息肉)将患者分为个体组。数据的统计评估采用 χ(2)检验。

结果

中位年龄为 50(26-85)岁,91 例患者为女性。在因 GP 诊断而行胆囊切除术的 138 例患者中,只有 99 例有组织病理学定义的息肉;其中 77 例为假息肉,22 例为真息肉。21 例患者患有腺癌。在这 21 例患者中,11 例为男性,中位年龄为 61(40-85)岁,所有恶性息肉直径均>10mm(P<0.0001)。在 138 例行手术的患者中,112 例有超声直径<10mm 的息肉。在其他 26 例直径>10mm 的患者中,22 例有真息肉。USG 对直径>10mm 的息肉的敏感性为 84.6%(P<0.0001);而对于直径<10mm 的息肉,敏感性仅为 66%。

结论

年龄大于 50 岁、直径大于 10mm 的单发息肉患者恶性肿瘤风险较高。

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