Alizad Azra, Whaley Dana H, Greenleaf James F, Fatemi Mostafa
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, 200 1st Street SW, Rochester, MN 55905, USA.
Ultrasonics. 2008 Nov;48(6-7):559-62. doi: 10.1016/j.ultras.2008.04.014. Epub 2008 May 25.
Vibro-acoustography is an imaging method based on audio-frequency harmonic vibrations induced in the object by the radiation force of focused ultrasound. The purpose of this study is to investigate features of vibro-acoustography images and manifestation of various tissue structures and calcifications in such images. Our motivation for this study is to pave the way for further in vitro and in vivo applications of vibro-acoustography. Here, vibro-acoustography images of excised prostate and in vivo breast are presented and compared with images obtained with other modalities. Resulting vibro-acoustography images obtained with a 3 MHz ultrasound transducer and at a vibration frequency of 50-60 kHz show soft tissue structures, tissue borders, and microcalcifications with high contrast, high resolution, and no speckle. It is concluded that vibro-acoustography offers features that may be valuable for diagnostic purposes.
振动声学造影是一种基于聚焦超声辐射力在物体中诱导产生音频谐波振动的成像方法。本研究的目的是探讨振动声学造影图像的特征以及此类图像中各种组织结构和钙化的表现。我们开展这项研究的动机是为振动声学造影在体外和体内的进一步应用铺平道路。在此,展示了切除前列腺的振动声学造影图像和体内乳房的振动声学造影图像,并与通过其他模态获得的图像进行比较。使用3兆赫超声换能器且在50 - 60千赫振动频率下获得的振动声学造影图像显示出软组织结构、组织边界和微钙化,具有高对比度、高分辨率且无斑点。得出的结论是,振动声学造影具有可能对诊断目的有价值的特征。