Mystakidou Kyriaki, Tsilika Eleni, Parpa Efi, Galanos Antonis, Vlahos Lambros
Pain Relief & Palliative Care Unit, Department of Radiology, Areteion Hospital, University of Athens, School of Medicine, Athens, Greece.
Cancer Nurs. 2008 Jul-Aug;31(4):326-32. doi: 10.1097/01.NCC.0000305749.50991.b1.
The present study aims to determine the use of Preparatory Grief in Advanced Cancer Patients (PGAC) Scale for screening preparatory grief according to independent criterion standards (ie, the Hospital Anxiety and Depression [HAD] Total scale and the HAD Depression and Anxiety subscales) and to establish an optimal cutoff point for discriminating between subjects with and without preparatory grief. One hundred advanced cancer patients treated in a Pain Relief and Palliative Care Unit completed the PGAC and HAD Scales, while researchers recorded data on demographic characteristics, disease status, and treatment regimen. Optimal balance between sensitivity and specificity for the PGAC Scale as a screening instrument was achieved at a cutoff score of 40+ for all the criterion standards (ie, HAD Total, HAD Anxiety, and HAD Depression), giving a sensitivity range between 84% and 92%, and specificity between 70% and 86%. The area under the receiver operating characteristic curve ranged between 0.867 and 0.968. The PGAC Scale had a favorable sensitivity and specificity in identifying cases of preparatory grief. The receiver operating characteristic analyses demonstrated that the scale is a useful screening instrument in advanced cancer patients.
本研究旨在根据独立的标准（即医院焦虑抑郁量表[HAD]总分以及HAD抑郁和焦虑分量表），确定晚期癌症患者预备性悲伤量表（PGAC）在筛查预备性悲伤方面的应用，并建立一个用于区分有或无预备性悲伤受试者的最佳临界点。在疼痛缓解与姑息治疗病房接受治疗的100名晚期癌症患者完成了PGAC和HAD量表，同时研究人员记录了人口统计学特征、疾病状况和治疗方案的数据。对于所有标准（即HAD总分、HAD焦虑和HAD抑郁），PGAC量表作为筛查工具在敏感度和特异度之间达到最佳平衡的临界点分数为40分及以上，敏感度范围在84%至92%之间，特异度在70%至86%之间。受试者工作特征曲线下面积在0.867至0.968之间。PGAC量表在识别预备性悲伤病例方面具有良好的敏感度和特异度。受试者工作特征分析表明，该量表在晚期癌症患者中是一种有用的筛查工具。
