Takeuchi Toshifumi, Hishiya Takayuki
Graduate School of Engineering, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan.
Org Biomol Chem. 2008 Jul 21;6(14):2459-67. doi: 10.1039/b715737c. Epub 2008 Apr 7.
This article gives the recent developments in molecular imprinting for proteins. Currently bio-macromolecules such as antibodies and enzymes are mainly employed for protein recognition purposes. However, such bio-macromolecules are sometimes difficult to find and/or produce, therefore, receptor-like synthetic materials such as protein-imprinted polymers have been intensively studied as substitutes for natural receptors. Recent advances in protein imprinting shown here demonstrate the possibility of this technique as a future technology of protein recognition.
本文介绍了蛋白质分子印迹技术的最新进展。目前，抗体和酶等生物大分子主要用于蛋白质识别目的。然而，这类生物大分子有时难以获取和/或生产，因此，蛋白质印迹聚合物等受体样合成材料作为天然受体的替代品受到了广泛研究。本文展示的蛋白质印迹技术的最新进展证明了该技术作为未来蛋白质识别技术的可能性。
