Zwetsloot C P, Caekebeke J F, Jansen J C, Odink J, Ferrari M D
Department of Clinical Neurophysiology, University Hospital, Leiden, The Netherlands.
Cephalalgia. 1991 May;11(2):103-7. doi: 10.1046/j.1468-2982.1991.1102103.x.
A pulsed Doppler device was used to measure blood flow velocities in the common carotid artery, the extracranial part of the internal carotid artery, the external carotid artery, the middle cerebral artery, and the anterior cerebral artery in 31 migraineurs without aura (n = 27) and with aura (n = 4), both during and outside an attack. The aims were to compare blood flow velocity during and between migraine attacks and to study asymmetries of the blood flow velocity. Compared with blood flow velocity values obtained in the attack-free interval, blood flow velocity was lower during attacks without aura in both common carotid arteries, but not in the other extra- and intracranial vessels which were examined. However, during attacks of migraine with aura, blood flow velocity tended to be lower in all examined vessels. There were no asymmetries of the blood flow velocity. We suggest that during migraine attacks without aura there is a dissociation in blood flow regulation in the common carotid and middle cerebral arteries.
使用脉冲多普勒装置测量了31名无先兆偏头痛患者(n = 27)和有先兆偏头痛患者(n = 4)在发作期间及发作间期颈总动脉、颈内动脉颅外段、颈外动脉、大脑中动脉和大脑前动脉的血流速度。目的是比较偏头痛发作期间和发作之间的血流速度,并研究血流速度的不对称性。与发作间期获得的血流速度值相比,无先兆偏头痛发作期间双侧颈总动脉的血流速度较低,但在其他检查的颅外和颅内血管中并非如此。然而,有先兆偏头痛发作期间,所有检查血管的血流速度都有降低的趋势。血流速度没有不对称性。我们认为,在无先兆偏头痛发作期间,颈总动脉和大脑中动脉的血流调节存在分离。