偏头痛和慢性紧张型头痛患者的脑血流速度
Cerebral blood flow velocity in migraine and chronic tension-type headache patients.
作者信息
Karacay Ozkalayci S, Nazliel B, Batur Caglayan H Z, Irkec C
机构信息
Department of Neurology, Faculty of Medicine, Gazi University, Ankara, Turkey.
出版信息
J Pain Res. 2018 Apr 4;11:661-666. doi: 10.2147/JPR.S144183. eCollection 2018.
INTRODUCTION
The present study seeks to use transcranial Doppler ultrasound to evaluate cerebral blood flow velocities in anterior and posterior circulation arteries, during an attack-free episode in migraine patients, with and without aura, as well as in chronic tension-type headache patients who were not receiving prophylactic medication.
METHODS
A total of 50 patients (35 female, 15 male) were evaluated during a headache-free episode: 30 migraine patients without aura (mean age: 32±8 years), 10 migraine patients with aura (mean age: 34±4 years), and 10 patients with chronic tension-type headache (mean age: 34±5 years).
RESULTS
No significant difference was present between anterior, middle, and posterior cerebral and vertebral arteries' blood flow velocities between migraine patients, with and without aura, or in patients with a tension-type headache, and normal controls (>0.05). However, a significant increase in basilar artery cerebral blood flow velocities relative to controls was present in patients with a tension-type headache (>0.001).
CONCLUSION
It is difficult to predict the main reason for the significant increase in basilar artery blood flow velocities in patients with chronic tension-type headache. It may be due to constriction of conductance or the dilatation of the resistance vessels.
引言
本研究旨在利用经颅多普勒超声评估偏头痛患者（有无先兆）在无发作期以及未接受预防性药物治疗的慢性紧张型头痛患者的前循环和后循环动脉的脑血流速度。
方法
在无头痛发作期对总共50例患者（35例女性，15例男性）进行评估：30例无先兆偏头痛患者（平均年龄：32±8岁），10例有先兆偏头痛患者（平均年龄：34±4岁），以及10例慢性紧张型头痛患者（平均年龄：34±5岁）。
结果
有无先兆的偏头痛患者或紧张型头痛患者与正常对照组相比，大脑前、中、后动脉以及椎动脉的血流速度无显著差异（>0.05）。然而，紧张型头痛患者的基底动脉脑血流速度相对于对照组显著增加（>0.001）。
结论
难以预测慢性紧张型头痛患者基底动脉血流速度显著增加的主要原因。这可能是由于传导血管收缩或阻力血管扩张所致。
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