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24例眼眶原发性非霍奇金淋巴瘤的临床与病理研究

[A clinical and pathological study of 24 cases of primary non-Hodgkin's lymphoma of the orbit].

作者信息

Qian H

机构信息

Institute of Cancer Research, Nanjing.

出版信息

Zhonghua Yan Ke Za Zhi. 1991 Mar;27(2):95-7.

PMID:1860413
Abstract

Primary non-Hodgkin's lymphoma of the orbit predominantly consists of the small lymphocytic, the lympho-plasmacytic, and the schistocytic types. Because of fair cellular differentiation, the tumor shows low or medium atypia as if benign. Hence, differential diagnosis from inflammation pseudotumor or lymphocytic hyperplasia is important. Follow-up of 18 of the present 24 cases showed that the tumor usually began insidiously and was long confined to the orbit. 44% (8/18) of the patients had relapses and 22% (4/18) died of systemic dissemination 2-6 years after confirmed diagnosis, a finding in agreement with Kinyh et al, who reported a 5 year survival rate of 75% and a 8 year survival rate of 50%. The prognosis was better than that of intranodal or extranodal non-Hodgkin's lymphoma in other locations.

摘要

眼眶原发性非霍奇金淋巴瘤主要由小淋巴细胞型、淋巴浆细胞型和裂细胞型组成。由于细胞分化良好,肿瘤表现出低度或中度异型性,看似良性。因此,与炎性假瘤或淋巴细胞增生进行鉴别诊断很重要。对本研究24例中的18例进行随访发现,肿瘤通常起病隐匿,长期局限于眼眶。确诊后2 - 6年,44%(8/18)的患者复发,22%(4/18)的患者死于全身播散,这一结果与Kinyh等人的报道一致,他们报告5年生存率为75%,8年生存率为50%。其预后优于其他部位的结内或结外非霍奇金淋巴瘤。

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