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[眼眶非霍奇金淋巴瘤的诊断困难]

[Difficulty in diagnosing an orbital non-Hodgkin's lymphoma].

作者信息

Drumare I, Rouland J F, Lenski C, Fenaux P, Fourrier P

出版信息

Bull Soc Ophtalmol Fr. 1989 Feb;89(2):315-8.

PMID:2805209
Abstract

History case of a patient treated for a bilateral orbital inflammatory pseudotumor has been rehospitalised for generalised lymphoma, despite the histological features of this tumor which evoked a pseudo-tumor. This error seems to be frequent because of the difficulties for the histological investigation of the tumor. Actually the application of immunohistochemical techniques and the study of immunoglobulin gene DNA rearrangement patterns allows the diagnosis. Often most of the orbital lymphomas, though apparently isolated, represent a localization of a systemic disease. Their treatment consists in either of radiotherapy in low grade malignancy localized cases or in chemotherapy in the others sometimes associated to radiotherapy.

摘要

一名曾因双侧眼眶炎性假瘤接受治疗的患者,尽管该肿瘤的组织学特征提示为假瘤,但因全身性淋巴瘤再次入院。由于肿瘤组织学检查存在困难,这种误诊似乎很常见。实际上,应用免疫组化技术以及研究免疫球蛋白基因DNA重排模式有助于诊断。通常,大多数眼眶淋巴瘤尽管看似孤立存在,但实际上是全身性疾病的局部表现。其治疗方法包括,对于低度恶性局限性病例采用放疗,对于其他病例有时联合放疗采用化疗。

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