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从基因组到蛋白质组:家蚕(Bombyx mori L.)研究取得巨大进展。

From genome to proteome: great progress in the domesticated silkworm (Bombyx mori L.).

作者信息

Zhou Zhonghua, Yang Huijuan, Zhong Boxiong

机构信息

College of Animal Sciences, Zhejiang University, Hangzhou 310029, China.

出版信息

Acta Biochim Biophys Sin (Shanghai). 2008 Jul;40(7):601-11. doi: 10.1111/j.1745-7270.2008.00432.x.

Abstract

As the only truly domesticated insect, the silkworm not only has great economic value, but it also has value as a model for genetics and molecular biology research. Genomics and proteomics have recently shown vast potential to be essential tools in domesticated silkworm research, especially after the completion of the Bombyx mori genome sequence. This paper reviews the progress of the domesticated silkworm genome, particularly focusing on its genetic map, physical map and functional genome. This review also presents proteomics, the proteomic technique and its application in silkworm research.

摘要

作为唯一真正被驯化的昆虫,家蚕不仅具有巨大的经济价值,还具有作为遗传学和分子生物学研究模型的价值。基因组学和蛋白质组学最近显示出巨大的潜力,有望成为家蚕研究中的重要工具,尤其是在家蚕基因组序列完成之后。本文综述了家蚕基因组的研究进展,特别关注其遗传图谱、物理图谱和功能基因组。本综述还介绍了蛋白质组学、蛋白质组学技术及其在家蚕研究中的应用。

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