Akutsu Toshinosuke, Saito Jun, Imai Ryota, Suzuki Tomoyuki, Cao Xiu Dong
Department of Mechanical Engineering, College of Engineering, Kanto Gakuin University, 1-50-1 Mutsuura-higashi, Yokohama, 236-8501, Japan.
J Artif Organs. 2008;11(2):75-90. doi: 10.1007/s10047-008-0410-y. Epub 2008 Jul 6.
The characteristics of mechanical bileaflet valves, the leaflets of which open at the outside first, differ significantly from those of natural valves, whose leaflets open at the center first, and this fact affects the flow field down-stream of the valves. The direction of jet-type flows, which is influenced by this difference in valve features, and the existence of the sinus of Valsalva both affect the flow field inside the aorta in different ways, depending on the valve design. There may also be an influence on the coronary circulation, the entrance to which resides inside the sinus of Valsalva. A dynamic particle image velocimetry (PIV) study was conducted to analyze the influence of the design of prosthetic heart valves on the aortic flow field. Three contemporary bileaflet prostheses, the St. Jude Medical (SJM) valve, the On-X valve (with straight leaflets), and the MIRA valve (with curved leaflets), were tested inside a simulated aorta under pulsatile flow conditions. A dynamic PIV system was employed to analyze the aortic flow field resulting from the different valve designs. The two newer valves, the On-X and the MIRA valves, open more quickly than the SJM valve and provide a wider opening area when the valve is fully open. The SJM valve's outer orifices deflect the flow during the accelerating flow phase, whereas the newer designs deflect the flow less. The flow through the central orifice of the SJM valve has a lower velocity compared to the newer designs; the newer designs tend to have a strong flow through all orifices. The On-X valve generates a simple jet-type flow, whereas the MIRA valve (with circumferentially curved leaflets) generates a strong but three-dimensionally diffuse flow, resulting in a more complex flow field downstream of the aortic valve. The clinically more adapted 180 degrees orientation seems to provide a less diffuse flow than the 90 degrees orientation does. The small differences in leaflet design in the bileaflet valves generate noticeable differences in the aortic flow; the newer valves show strong flows through all orifices.
双叶机械瓣膜的瓣叶首先在外侧打开,其特性与天然瓣膜显著不同,天然瓣膜的瓣叶首先在中心打开,这一事实影响了瓣膜下游的流场。受瓣膜特性差异影响的喷射流方向以及主动脉窦的存在,都会根据瓣膜设计以不同方式影响主动脉内的流场。这也可能会对冠状动脉循环产生影响,冠状动脉的入口位于主动脉窦内。进行了一项动态粒子图像测速(PIV)研究,以分析人工心脏瓣膜设计对主动脉流场的影响。在脉动流条件下,对三种当代双叶人工瓣膜——圣犹达医疗(SJM)瓣膜、On-X瓣膜(瓣叶为直线型)和MIRA瓣膜(瓣叶为曲线型)在模拟主动脉内进行了测试。采用动态PIV系统分析不同瓣膜设计产生的主动脉流场。两种新型瓣膜,即On-X瓣膜和MIRA瓣膜,比SJM瓣膜打开得更快,并且在瓣膜完全打开时提供更宽的开口面积。在加速流阶段,SJM瓣膜的外部孔口会使血流发生偏转,而新型设计的瓣膜使血流偏转的程度较小。与新型设计相比,通过SJM瓣膜中心孔口的血流速度较低;新型设计往往在所有孔口都有强劲的血流。On-X瓣膜产生简单的喷射流,而MIRA瓣膜(瓣叶为周向曲线型)产生强烈但三维扩散的血流,导致主动脉瓣下游的流场更加复杂。临床上更适用的180度取向似乎比90度取向产生的血流扩散程度更小。双叶瓣膜瓣叶设计的微小差异在主动脉血流中产生了显著差异;新型瓣膜在所有孔口都显示出强劲的血流。