逆转早衰。 - Suppr

Suppr

超能文献

Rejuvenating premature aging.

作者信息

Meshorer Eran, Gruenbaum Yosef

出版信息

Nat Med. 2008 Jul;14(7):713-5. doi: 10.1038/nm0708-713.

DOI:10.1038/nm0708-713

PMID:18607367

Abstract

摘要

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Rejuvenating premature aging.逆转早衰。

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引用本文的文献

Nuclear organization and regulation of the differentiated state.核组织与分化状态的调控。

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Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease.层粘连相关多肽（LAP）2α与核纤层蛋白在成体干细胞调控及疾病中的作用

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DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome.亨廷顿氏舞蹈症-吉福德早衰症中的 DNA 损伤积累和复制停滞。

Biochem Soc Trans. 2011 Dec;39(6):1764-9. doi: 10.1042/BST20110687.

Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells.法尼基转移酶抑制剂治疗可恢复亨廷顿病-吉尔福德早衰综合征细胞中的染色体区位置和活性染色体动力学。

Genome Biol. 2011 Aug 12;12(8):R74. doi: 10.1186/gb-2011-12-8-r74.

Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.早老症中因前体核纤层蛋白A成熟缺陷导致的基因组不稳定和DNA损伤反应。

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