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[术后急性二尖瓣反流。非心脏小手术后的意外发现]

[Postoperative acute mitral regurgitation. Unexpected finding after minor non-cardiac surgery].

作者信息

Wagner K J, Unterbuchner C, Bogdanski R, Martin J, Kochs E F, Tassani-Prell P

机构信息

Klinik für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675 München, Deutschland.

出版信息

Anaesthesist. 2008 Oct;57(10):976-81. doi: 10.1007/s00101-008-1409-8.

Abstract

This report describes the case of a 59-year-old man who was scheduled for general anesthesia with propofol, sufentanil and sevoflurane for removal of a metal implant. The patient was classified as American Society of Anesthesiologists (ASA) II status because of an asymptomatic mitral valve prolapse and medically treated arterial hypertension. During induction of narcosis a pulsoxymetrically measured inadequate increase in oxygen saturation after preoxygenation was noticed and a moderate respiratory obstruction occurred intraoperatively, but anesthesia was uneventfully completed and the patient was extubated. However, 3 h later the patient developed severe dyspnea, hypoxia, tachycardia and arterial hypotension. Physical examination revealed a new grade 4/6 systolic murmur radiating to the axilla and X-ray showed bilateral pulmonary edema. Neither electrocardiographic nor biochemical manifestations of acute myocardial infarction were identified but transthoracic echocardiography revealed fluttering of the posterior leaflet of the mitral valve with grade III regurgitation and dilation of the left atrium. Coronary angiography was normal and left ventriculography confirmed severe mitral regurgitation. Mitral valve repair was successfully performed 22 h after presentation of symptoms. Mitral regurgitation is a common finding on echocardiography, seen to some degree in over 75% of the population. The etiology of mitral valve insufficiency which can be caused by pathologic changes of one or more of the components of the mitral valve, including the leaflets, annulus, chordae tendineae, papillary muscles, or by abnormalities of the surrounding left ventricle and/or atrium are discussed. Rupture of mitral chordae tendineae is infrequent and causes acute hemodynamic deterioration and needs corrective surgery. Valve replacement should be performed only if mitral valve repair is not possible. Echocardiography is an invaluable tool in determining the severity of regurgitation, the integrity of the mitral valve apparatus, the extent of left ventricular enlargement, and the ejection fraction. Acute mitral valve regurgitation caused by a rupture of chordae tendineae should be considered in the differential diagnosis of perioperative acute pulmonary edema.

摘要

本报告描述了一名59岁男性的病例,该患者计划接受丙泊酚、舒芬太尼和七氟醚全身麻醉以取出金属植入物。由于无症状二尖瓣脱垂和药物治疗的动脉高血压,该患者被分类为美国麻醉医师协会(ASA)II级。在麻醉诱导期间,注意到预给氧后经脉搏血氧饱和度测定的氧饱和度增加不足,术中出现中度呼吸阻塞,但麻醉顺利完成且患者拔管。然而,3小时后患者出现严重呼吸困难、缺氧、心动过速和动脉低血压。体格检查发现新出现的4/6级收缩期杂音向腋窝传导,X线显示双侧肺水肿。未发现急性心肌梗死的心电图或生化表现,但经胸超声心动图显示二尖瓣后叶扑动伴III级反流和左心房扩张。冠状动脉造影正常,左心室造影证实严重二尖瓣反流。症状出现22小时后成功进行了二尖瓣修复。二尖瓣反流是超声心动图上的常见表现,在超过75%的人群中在某种程度上可见。讨论了二尖瓣关闭不全的病因,其可由二尖瓣的一个或多个组成部分的病理变化引起,包括瓣叶、瓣环、腱索、乳头肌,或由周围左心室和/或心房的异常引起。二尖瓣腱索断裂不常见,会导致急性血流动力学恶化,需要进行矫正手术。仅在无法进行二尖瓣修复时才应进行瓣膜置换。超声心动图在确定反流严重程度、二尖瓣装置完整性、左心室扩大程度和射血分数方面是一种非常有价值的工具。围手术期急性肺水肿的鉴别诊断中应考虑由腱索断裂引起的急性二尖瓣反流。

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