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与普通人群相比,甲基苯丙胺使用者的身体健康受损情况:甲基苯丙胺依赖和阿片类药物使用的作用。

Impaired physical health among methamphetamine users in comparison with the general population: the role of methamphetamine dependence and opioid use.

作者信息

McKetin Rebecca, Kelly Erin, McLaren Jennifer, Proudfoot Heather

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, Sydney 2052 NSW, Australia.

出版信息

Drug Alcohol Rev. 2008 Sep;27(5):482-9. doi: 10.1080/09595230801914776.

Abstract

AIM

To examine the extent of physical health impairment among a community sample of methamphetamine users in comparison with the general population, and factors associated with impairment among this group.

METHOD

A cross-sectional survey of 309 regular methamphetamine users from Sydney. The Physical Component Scale of the Short Form 12 (SF-12) was used to measure impairment in physical health (score < 40). Age-matched general population data for the SF-12 were derived from the Australian National Survey of Mental Health and Well-Being.

RESULTS

Participants had a higher prevalence of impaired physical health compared to the Australian general population (20% vs. 10%, p<0.05), but this effect occurred among only dependent methamphetamine users over 24 years of age (25 - 34 years, 23% vs. 10%; 35 - 44 years, 41% vs. 12%). Methamphetamine dependence remained significantly predictive of impaired physical health after adjusting for age and other confounding factors. Opioid pharmacotherapy was also related strongly to poor physical health, accounting for 63% of participants with physical impairment. Other factors associated with impaired physical health were being female, having less than 10 years of schooling, and having been diagnosed previously with an anxiety disorder (p<0.05).

CONCLUSION

Methamphetamine users are more likely to report impaired physical health than the general population, but this impairment is specific to older methamphetamine users who are dependent on the drug, particularly those who are enrolled in opioid pharmacotherapy.

摘要

目的

与普通人群相比,研究甲基苯丙胺使用者社区样本中的身体健康损害程度,以及该群体中与损害相关的因素。

方法

对来自悉尼的309名甲基苯丙胺常规使用者进行横断面调查。使用简短健康调查问卷12项版(SF - 12)的身体成分量表来测量身体健康损害情况(得分<40)。SF - 12的年龄匹配普通人群数据来自澳大利亚全国心理健康与幸福调查。

结果

与澳大利亚普通人群相比,参与者身体健康受损的患病率更高(20%对10%,p<0.05),但这种影响仅发生在24岁以上的依赖甲基苯丙胺使用者中(25 - 34岁,23%对10%;35 - 44岁,41%对12%)。在调整年龄和其他混杂因素后,甲基苯丙胺依赖仍然是身体健康受损的显著预测因素。阿片类药物治疗也与身体健康不佳密切相关,占身体受损参与者的63%。与身体健康受损相关的其他因素包括女性、受教育年限少于10年以及先前被诊断患有焦虑症(p<0.05)。

结论

与普通人群相比,甲基苯丙胺使用者更有可能报告身体健康受损,但这种损害特定于依赖该药物的老年甲基苯丙胺使用者,尤其是那些接受阿片类药物治疗的人。

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