McKetin Rebecca, Kelly Erin, McLaren Jennifer
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, 2052 NSW, Australia.
Drug Alcohol Depend. 2006 Dec 1;85(3):198-204. doi: 10.1016/j.drugalcdep.2006.04.007. Epub 2006 May 24.
The aim of the current study was to determine whether crystalline methamphetamine users are more dependent on methamphetamine than people who use other forms of the drug, and if so, whether this could be accounted for by their methamphetamine use history.
A structured face-to-face interview was used to assess drug use patterns and demographics among a convenience sample of 309 regular methamphetamine users from Sydney, Australia. Dependence on methamphetamine in the past year was measured using the Severity of Dependence Scale. The use of crystalline methamphetamine in the past year was confirmed using a photographic identification sheet.
Participants who had used crystalline methamphetamine in the past year were significantly more likely to be dependent on methamphetamine than participants who took only other forms of methamphetamine during this time (61% versus 39%). Methamphetamine dependence was also associated with injecting or smoking methamphetamine (67% and 58%, respectively versus 30% for intranasal or oral use), using methamphetamine more than weekly (68% versus 34%), having used the drug for more than 5 years (61% versus 36%), and having used 'base' methamphetamine in the past year (59% versus 39%). Crystalline methamphetamine use remained significantly associated with methamphetamine dependence after adjusting for these patterns of methamphetamine use.
Methamphetamine users who took crystalline methamphetamine in the past year were more likely to be dependent than methamphetamine users who had not taken the crystalline form of the drug during this time.
本研究的目的是确定使用冰毒的人是否比使用其他形式甲基苯丙胺的人对甲基苯丙胺更依赖,如果是这样,这是否可以用他们的甲基苯丙胺使用史来解释。
采用结构化面对面访谈,对来自澳大利亚悉尼的309名常规甲基苯丙胺使用者的便利样本进行药物使用模式和人口统计学评估。使用依赖严重程度量表测量过去一年中对甲基苯丙胺的依赖程度。使用照片识别表确认过去一年中是否使用过冰毒。
过去一年中使用过冰毒的参与者比在此期间仅使用其他形式甲基苯丙胺的参与者更有可能对甲基苯丙胺产生依赖(分别为61%和39%)。甲基苯丙胺依赖还与注射或吸食甲基苯丙胺有关(分别为67%和58%,而鼻内或口服使用为30%),每周使用甲基苯丙胺超过一次(68%对34%),使用该药物超过5年(61%对36%),以及在过去一年中使用过“基础”甲基苯丙胺(59%对39%)。在对这些甲基苯丙胺使用模式进行调整后,冰毒使用与甲基苯丙胺依赖仍显著相关。
过去一年中使用过冰毒的甲基苯丙胺使用者比在此期间未使用过该晶体形式药物的甲基苯丙胺使用者更有可能产生依赖。