Qureshi Abrar A, Dominguez Patrick, Duffin Kristina C, Gladman Dafna D, Helliwell Philip, Mease Philip J, Husni M Elaine
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
J Rheumatol. 2008 Jul;35(7):1423-5.
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis, with an indolent and progressive course. A delay in diagnosis and treatment may lead to an erosive arthropathy, leading further to physical disability and deformity. To help clinicians screen for PsA, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) has led an effort to develop and validate 3 PsA screening tools. Administration of a well designed screening tool can increase detection of PsA, help determine the prevalence of PsA in a given population, record clinical data for genotype-phenotype studies, and track response to therapy. The development and validation of these screening tools was a major focus at the GRAPPA annual meeting at Boston in September 2007; we summarize that portion of the meeting.
银屑病关节炎(PsA)是一种与银屑病相关的炎性关节炎,病程隐匿且呈进行性发展。诊断和治疗的延迟可能导致侵蚀性关节病,进而导致身体残疾和畸形。为帮助临床医生筛查PsA,银屑病和银屑病关节炎研究与评估小组(GRAPPA)致力于开发和验证3种PsA筛查工具。使用精心设计的筛查工具可提高PsA的检出率,有助于确定特定人群中PsA的患病率,记录用于基因型-表型研究的临床数据,并跟踪治疗反应。这些筛查工具的开发和验证是2007年9月在波士顿举行的GRAPPA年会上的一个主要焦点;我们总结了该会议的这部分内容。