Busse Kristine, Liao Wilson
Department of Dermatology and Psoriasis Treatment Center, University of California-San Francisco, San Francisco, California.
Psoriasis Forum. 2010 Winter;16(4):17-25.
Psoriatic arthritis is a major comorbidity of psoriasis that significantly impairs quality of life and physical function. Because skin lesions classically precede joint symptoms, dermatologists are in a unique position to identify patients at risk for psoriatic arthritis before irreversible joint damage occurs. Here we review the literature to identify the clinical and genetic factors most highly associated with development of psoriatic arthritis, with the goal of assisting dermatologists in risk-stratifying their psoriasis patients.
银屑病关节炎是银屑病的一种主要合并症,会显著损害生活质量和身体功能。由于皮肤病变通常先于关节症状出现,皮肤科医生处于独特地位,能够在不可逆转的关节损伤发生之前识别出有银屑病关节炎风险的患者。在此,我们回顾文献,以确定与银屑病关节炎发生最密切相关的临床和遗传因素,目的是帮助皮肤科医生对银屑病患者进行风险分层。