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[乙烯信号转导途径]

[Ethylene signal transduction pathway].

作者信息

Frankowski Kamil, Kesy Jacek, Kotarba Wojciech, Kopcewicz Jan

机构信息

Zakład Fizjologii i Biologii Molekularnej Roślin, Instytut Biologii Ogólnej i Molekularnej, Uniwersytet Mikołaja Kopernika, Toruń.

出版信息

Postepy Biochem. 2008;54(1):99-106.

Abstract

Ethylene is involved in the regulation of many growth and developmental processes in plants. Signaling pathways of the hormone are activated by five receptors, which are localized in membranes of endoplasmic reticulum and are similar to bacterial two-component histidine kinases. In the air, ethylene receptors activate CTR1 protein, which is a negative regulator (repressor) of nuclear protein--EIN2. In turn, EIN2 is an activator of transcriptional factors cascade responsible for the regulation of the expression of ethylene response genes. The level of EIN3, as well as other elements of ethylene signal transduction pathway, is subjected to complicated regulations on transcriptional and posttranslational levels, in which other internal and environmental factors are involved.

摘要

乙烯参与植物许多生长和发育过程的调控。该激素的信号通路由五种受体激活,这些受体定位于内质网膜上,与细菌双组分组氨酸激酶相似。在空气中,乙烯受体激活CTR1蛋白,CTR1蛋白是核蛋白EIN2的负调控因子(阻遏物)。反过来,EIN2是负责调控乙烯反应基因表达的转录因子级联反应的激活剂。EIN3的水平以及乙烯信号转导途径的其他元件,在转录和翻译后水平上受到复杂的调控,其中涉及其他内部和环境因素。

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