Huang Lii-Shung, Lee Maw-Sheng, Cheng En-Hui, Lee Tsung-Hsien, Liu Chung-Hsien, Lee Meng-Chih, Chou Ming-Chih
Institute of Medicine, College of Medicine, Chung-Shan Medical University, Taichung, Taiwan, Republic of China.
Reprod Biomed Online. 2008 Jul;17(1):94-100. doi: 10.1016/s1472-6483(10)60299-4.
Successful embryo implantation depends on interactions between the embryo and the uterus. Investigating factors related to the recipients in an oocyte donation programme could therefore improve the overall pregnancy outcome. In this study, the factors that affect outcomes following IVF after oocyte donation were evaluated in a retrospective cohort study. A total of 143 cycles were evaluated. All oocyte donors were younger than 30 years of age. In the youngest recipients (< 34 years old) the implantation rate was higher (P = 0.042) and the abortion rate was apparently lower than in the recipients of more advanced age (> or =40 years old). The implantation and pregnancy rates were higher when the pulsatility index was > or = 3.0. The pulsatility index on the day of embryo transfer in oocyte donation IVF cycles was an important determinant of successful pregnancy outcomes.
成功的胚胎着床取决于胚胎与子宫之间的相互作用。因此，在卵母细胞捐赠计划中研究与受体相关的因素可以改善整体妊娠结局。在这项研究中，通过一项回顾性队列研究评估了影响卵母细胞捐赠后体外受精结局的因素。共评估了143个周期。所有卵母细胞捐赠者年龄均小于30岁。在最年轻的受体（<34岁）中，着床率较高（P = 0.042），流产率明显低于年龄较大的受体（≥40岁）。当搏动指数≥3.0时，着床率和妊娠率较高。卵母细胞捐赠体外受精周期中胚胎移植当天的搏动指数是成功妊娠结局的重要决定因素。
