Aslam Muhammad, Inayat Musaddaq
Department of Pediatrics and Division of Newborn Medicine, Harvard Neonatal-Perinatal Fellowship Program, Children's Hospital Boston, Boston, MA, USA.
South Med J. 2008 Aug;101(8):840-1. doi: 10.1097/SMJ.0b013e31817dae27.
Fetal and neonatal thyrotoxicosis from maternal Graves disease is a very rare entity. Fetal symptoms result from the transplacental passage of thyroid-stimulating immunoglobulins, which persist in the neonate resulting in neonatal symptoms. We present a case of fetal and neonatal thyrotoxicosis from maternal Graves disease. Fetal symptoms were controlled with maternal administration of antithyroid drugs leading to fetal thyroid inhibition. We present this case with a brief review of the literature.
母体格雷夫斯病所致胎儿及新生儿甲状腺毒症是一种非常罕见的病症。胎儿症状源于促甲状腺素免疫球蛋白经胎盘传递，该物质在新生儿体内持续存在从而导致新生儿出现症状。我们报告一例母体格雷夫斯病所致胎儿及新生儿甲状腺毒症病例。通过母体服用抗甲状腺药物抑制胎儿甲状腺，胎儿症状得到控制。我们结合文献简要介绍此病例。
