Bahna S L, Kanuga J
Department of Allergy and Immunology, Cleveland Clinic Foundation, Ohio.
Rheum Dis Clin North Am. 1991 May;17(2):243-9.
Food allergy is one of several causes of adverse reactions to foods. The underlying immunologic mechanism varies from one manifestation to another, hence no current single laboratory test can be expected to be positive in every case. The diagnosis could be suggested by information gathered from the medical history or screening procedures, such as trials of elimination diets, the food/symptom diary, skin testing, and in vitro-specific IgE antibody measurement. All foods suspected by any of the aforementioned methods should be subjected to verification by appropriate elimination-challenge testing, preferably in a double-blind, placebo-controlled manner. Basically, treatment is dietary elimination, and its success requires identification and avoidance of all offending foods and control of other contributory factors.
食物过敏是食物不良反应的几种原因之一。潜在的免疫机制因表现形式而异,因此目前没有一种单一的实验室检测能在每种情况下都呈阳性。根据病史或筛查程序收集的信息,如排除饮食试验、食物/症状日记、皮肤试验和体外特异性IgE抗体测量,可提示诊断。通过上述任何一种方法怀疑的所有食物都应通过适当的排除激发试验进行验证,最好采用双盲、安慰剂对照的方式。基本上,治疗方法是饮食排除,其成功需要识别并避免所有引起问题的食物,并控制其他促成因素。