Northrop R L, Deinhardt F
Department of Microbiology, Presbyterian-St. Luke's Hospital, Medical and Graduate Schools, University of Illinois, Chicago, Illinois 60612, USA.
J Natl Cancer Inst. 1967 Oct;39(4):685-9.
Three hundred and fifty-six bone marrow tissues obtained from patients of a general hospital were tested for spontaneous production after cultivation in vitro of interferon-like substances (ILS). Seventeen percent of the tissues produced ILS that protected human, but not chick, embryo cell cultures against the cytopathic effects of challenge virus infection. The incidence of ILS did not correlate with leukemia or other neoplastic diseases, or with any non-neoplastic disease.
从一家综合医院的患者身上获取了356份骨髓组织，对其进行体外培养后检测类干扰素物质（ILS）的自发产生情况。17%的组织产生了ILS，这些ILS可保护人胚细胞培养物，但不能保护鸡胚细胞培养物免受攻击病毒感染的细胞病变效应影响。ILS的发生率与白血病或其他肿瘤性疾病，以及任何非肿瘤性疾病均无相关性。
