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口腔扁平苔藓的报告患病率:综述与评论

The reported prevalence of oral lichen planus: a review and critique.

作者信息

McCartan B E, Healy C M

机构信息

Department of Anatomy, Faculty of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.

出版信息

J Oral Pathol Med. 2008 Sep;37(8):447-53. doi: 10.1111/j.1600-0714.2008.00662.x. Epub 2008 Jul 9.

Abstract

OBJECTIVE

To examine all studies reporting prevalences of oral lichen planus (OLP) for epidemiological validity and to extract prevalence data from the valid papers.

DESIGN

Computer based literature searches were carried out using the MeSH headings 'lichen planus, oral and (prevalence or incidence)' and were supplemented by manual searching.

MAIN OUTCOME MEASURES

Each paper was examined for five criteria: clinic-based or population study, adequate demographic description (by sex and age group) of the population, adequate demographic description of the sample (if the population was sampled), adequate demographic description of the OLP cases identified, and histological confirmation of the clinical diagnosis.

RESULTS

Forty-five relevant papers were identified, 21 clinic-based and 24 population studies. All but one of the population studies was deficient. One study, while having some defects, was probably sufficiently valid to permit the findings to be regarded as useful. An overall age-standardized prevalence of 1.27% (0.96% in men and 1.57% in women) can be calculated from this study.

CONCLUSIONS

There appears to be only one usable prevalence study of OLP. Other large-scale studies are required in other populations. Such studies need to distinguish between OLP and lichenoid reactions.

摘要

目的

审查所有报告口腔扁平苔藓(OLP)患病率的研究,以评估其流行病学有效性,并从有效论文中提取患病率数据。

设计

使用医学主题词“扁平苔藓,口腔的和(患病率或发病率)”进行基于计算机的文献检索,并辅以手工检索。

主要观察指标

检查每篇论文是否符合五个标准:基于诊所的研究或人群研究、对人群进行充分的人口统计学描述(按性别和年龄组)、对样本进行充分的人口统计学描述(如果对人群进行了抽样)、对所识别的OLP病例进行充分的人口统计学描述以及对临床诊断进行组织学确认。

结果

共识别出45篇相关论文,其中21篇基于诊所的研究,24篇人群研究。除一项人群研究外,其他所有研究均存在缺陷。一项研究虽然存在一些缺陷,但可能具有足够的有效性,其结果可被视为有用。根据这项研究,可以计算出总体年龄标准化患病率为1.27%(男性为0.96%,女性为1.57%)。

结论

似乎只有一项关于OLP的可用患病率研究。其他人群需要进行其他大规模研究。此类研究需要区分OLP和苔藓样反应。

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