Huo Changhong, Liang Hong, Tu Guangzhong, Zhao Yuying, Lin Wenhan
Department of Natural Medicines and the State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, P. R. China.
Nat Prod Res. 2008;22(10):896-900. doi: 10.1080/14786410701642680.
From a China mangrove plant Acanthus ilicifolius Linn., a new compound, 5,11-epoxymegastigmane glucoside (1) was isolated along with one known compound of megastigmane glucosides, (6S, 9S)-roseoside (2). The structure of compound 1 was determined on the basis of 1D- and 2D-NMR techniques (DEPT, COSY, HMBC, HMQC, NOESY) and HR-FABMS. The structure of 1 was established as (1S, 3S, 5R, 6R, 7E)-5,11-epoxy-3-hydroxymegastigman-7-en-9-one-3-O-beta-D-glucopyranoside.
从中国红树植物老鼠簕中分离得到一个新化合物5,11-环氧巨大戟烷糖苷（1）以及一个已知的巨大戟烷糖苷类化合物（6S, 9S）-蔷薇糖苷（2）。化合物1的结构通过一维和二维核磁共振技术（DEPT、COSY、HMBC、HMQC、NOESY）以及高分辨快原子轰击质谱得以确定。1的结构确定为(1S, 3S, 5R, 6R, 7E)-5,11-环氧-3-羟基巨大戟-7-烯-9-酮-3-O-β-D-吡喃葡萄糖苷。
