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睡眠药物使用的种族差异:约翰斯顿县骨关节炎项目的横断面研究

Racial differences in sleep medication use: a cross-sectional study of the Johnston County Osteoarthritis Project.

作者信息

Allen Kelli D, Renner Jordan B, DeVellis Brenda, Helmick Charles G, Jordan Joanne M

机构信息

Department of Medicine, Health Services Research and Development Service, Durham Veterans Affairs Medical Center, Duke University Medical Center, Durham, NC 27705, USA.

出版信息

Ann Pharmacother. 2008 Sep;42(9):1239-46. doi: 10.1345/aph.1L111. Epub 2008 Jul 15.

Abstract

BACKGROUND

Little is known about racial differences in the use of sleep medications.

OBJECTIVES

To compare sleep medication use among African Americans and whites with self-reported current sleep problems.

METHODS

Participants were 1910 individuals (69% female, 34% African American, 66% white) from the Johnston County Osteoarthritis Project. We examined racial differences in self-reported current use of prescription, nonprescription, herbal, and other medications for sleep. Multivariable logistic regression models controlled for age, sex, education, health insurance, symptomatic hip or knee osteoarthritis, depressive symptoms, obesity, fair or poor general health, and self-reported annual days of sleep problems. Models were conducted separately for the whole sample and for men and women.

RESULTS

Among participants with current sleep problems, 31% were using one or more types of sleep medication: 17% prescription, 12% nonprescription, 1% herbal, and 3% other products. African Americans were less likely than whites to be using any sleep medication (25% vs 35%; p < 0.001), prescription sleep medication (14% vs 19%; p = 0.003), and nonprescription sleep medication (10% vs 13%; p = 0.048). These racial differences persisted in multivariable models. In sex-stratified analyses, there were significant racial differences in sleep medication use only among women.

CONCLUSIONS

African Americans were less likely than whites to report current use of prescription and nonprescription sleep medications; these results appeared to be largely driven by racial differences among women. Additional research should study possible underlying factors and determine whether these racial differences impact clinical outcomes.

摘要

背景

关于睡眠药物使用方面的种族差异,人们了解甚少。

目的

比较非裔美国人和白人中自我报告存在当前睡眠问题者的睡眠药物使用情况。

方法

研究对象为来自约翰斯顿县骨关节炎项目的1910名个体(69%为女性,34%为非裔美国人,66%为白人)。我们研究了自我报告的当前使用处方、非处方、草药及其他睡眠药物方面的种族差异。多变量逻辑回归模型对年龄、性别、教育程度、健康保险、有症状的髋或膝骨关节炎、抑郁症状、肥胖、一般健康状况良好或较差以及自我报告的每年睡眠问题天数进行了控制。模型分别针对整个样本以及男性和女性进行。

结果

在当前存在睡眠问题的参与者中,31%正在使用一种或多种类型的睡眠药物:17%使用处方药物,12%使用非处方药物,1%使用草药,3%使用其他产品。非裔美国人使用任何睡眠药物(25%对35%;p<0.001)、处方睡眠药物(14%对19%;p = 0.003)和非处方睡眠药物(10%对13%;p = 0.048)的可能性均低于白人。这些种族差异在多变量模型中仍然存在。在按性别分层的分析中,仅在女性中睡眠药物使用存在显著的种族差异。

结论

非裔美国人报告当前使用处方和非处方睡眠药物的可能性低于白人;这些结果似乎在很大程度上是由女性中的种族差异所驱动。进一步的研究应探讨可能的潜在因素,并确定这些种族差异是否会影响临床结局。

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