Pogodin O K, Samorodinova L A, Matveeva N K, Sukhikh G T
Akush Ginekol (Mosk). 1991 Apr(4):40-4.
A clinicoimmunological examination was performed in 70 patients with acute inflammatory disease of internal genitalia. All the patients received a multimodality anti-inflammatory therapy. They were divided into 2 groups: 1) 30 patients taking ++T-activin as an adjuvant and 2) 40 patients untreated with it. T and B lymphocytes were measured by current cytofluorometry+ by means of monoclonal antibodies and the rosette-forming method. A subpopulation analysis of the T-cell immune system revealed lower T-helper count and decreased immunoregulatory index. ++T-activin used in the multimodality therapy for acute inflammatory diseases of internal genitalia improved the qualitative parameters of regulatory T-cell subpopulations, returned T and B lymphocytes to normal levels and elevated IgG concentrations.
对70例内生殖器急性炎症性疾病患者进行了临床免疫学检查。所有患者均接受了多模式抗炎治疗。他们被分为两组：1）30例患者使用++T-激活素作为辅助治疗，2）40例患者未使用该药物。通过当前的细胞荧光测定法，借助单克隆抗体和玫瑰花结形成法对T和B淋巴细胞进行检测。T细胞免疫系统的亚群分析显示辅助性T细胞数量减少，免疫调节指数降低。在多模式治疗内生殖器急性炎症性疾病中使用的++T-激活素改善了调节性T细胞亚群的质量参数，使T和B淋巴细胞恢复到正常水平，并提高了IgG浓度。
