Sakhelashvili-Haladzhun M I
Lik Sprava. 1994 Sep-Dec(9-12):103-5.
The paper presents results of the in vitro study of the immunomodulating effect of T-activin in 54 patients with active primary pulmonary tuberculosis, with the purpose of establishing criteria for initiating the therapy with this preparation. The most sensitive test for the determination of immunomodulating effect of T-activin in vitro appeared to be the reaction of active rosette forming (Ea-RFCs). The investigations performed showed that the preparation of the thymus gland can be recommended for use in those patients only, in whom there is striking or moderate decrease in the count of active RFCs. In the presence of their normal content T-activin may bring about depression of cellular immunity.
本文介绍了对54例活动性原发性肺结核患者进行的T-激活素免疫调节作用的体外研究结果，目的是确定开始使用该制剂治疗的标准。体外测定T-激活素免疫调节作用最敏感的试验似乎是活性玫瑰花结形成反应（Ea-RFCs）。所进行的研究表明，仅在活性RFC计数显著或中度降低的患者中，可推荐使用胸腺制剂。当活性RFC含量正常时，T-激活素可能会导致细胞免疫抑制。
